Transcription Factor

Accessions: 1bl0_A (3D-footprint 20231221)
Names: MARA_ECOLI, MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0ACH5
Length: 116
Pfam Domains: 12-53 Bacterial regulatory helix-turn-helix proteins, AraC family
26-102 Helix-turn-helix domain
65-102 Bacterial regulatory helix-turn-helix proteins, AraC family
Sequence:
(in bold interface residues)
1 DAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEI 60
61 AQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDVPPHKYRMTNMQGESRFLHPL
Interface Residues: 32, 33, 34, 35, 37, 38, 41, 83, 84, 87, 88, 92
3D-footprint Homologues: 3w6v_A, 4hf1_A, 7vwz_G, 1xs9_A, 1zgw_A
Binding Motifs: 1bl0_A TTnGCAnnnnGTGGC
Binding Sites: 1bl0_B
1bl0_C
Publications: Rhee S., Martin RG., Rosner JL., Davies DR. A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator. Proc Natl Acad Sci U S A. 95(18):10413-8 (1998). [Pubmed]
Related annotations: PaperBLAST

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