Transcription Factor
| Accessions: | 4a04_A (3D-footprint 20231221) |
| Names: | T-box protein 1, T-BOX TRANSCRIPTION FACTOR TBX1, TBX1_HUMAN, Testis-specific T-box protein |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | O43435 |
| Length: | 181 |
| Pfam Domains: | 4-181 T-box |
| Sequence: (in bold interface residues) | 1 GVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDK 60 61 RYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGH 120 121 IILNSMHRYQPRFHVVYVDPRENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFR 180 181 D |
| Interface Residues: | 29, 158, 159, 175, 178, 179 |
| 3D-footprint Homologues: | 5flv_I, 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B |
| Binding Motifs: | 4a04_AB TnnnCACcnaGgTGnnnA |
| Publications: | El Omari K, De Mesmaeker J, Karia D, Ginn H, Bhattacharya S, Mancini E.J. Structure of the DNA-bound T-box domain of human TBX1, a transcription factor associated with the DiGeorge syndrome. Proteins : (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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