Transcription Factor
| Accessions: | Q8N883 (JASPAR 2024) |
| Names: | ZN614_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8N883 |
| Length: | 585 |
| Pfam Domains: | 8-48 KRAB box 274-297 Zinc-finger double domain 287-309 C2H2-type zinc finger 287-309 Zinc finger, C2H2 type 289-310 C2H2-type zinc finger 304-325 Zinc-finger double domain 315-337 Zinc finger, C2H2 type 315-337 C2H2-type zinc finger 315-337 C2H2-type zinc finger 329-353 Zinc-finger double domain 343-365 Zinc finger, C2H2 type 343-365 C2H2-type zinc finger 343-354 C2H2-type zinc finger 358-381 Zinc-finger double domain 371-393 Zinc finger, C2H2 type 371-393 C2H2-type zinc finger 373-393 C2H2-type zinc finger 385-409 Zinc-finger double domain 399-421 Zinc finger, C2H2 type 399-421 C2H2-type zinc finger 414-438 Zinc-finger double domain 427-449 C2H2-type zinc finger 427-449 C2H2-type zinc finger 427-449 Zinc finger, C2H2 type 444-465 Zinc-finger double domain 454-477 C2H2-type zinc finger 455-477 C2H2-type zinc finger 472-494 Zinc-finger double domain 483-505 C2H2-type zinc finger 483-503 C2H2-type zinc finger 483-505 Zinc finger, C2H2 type 499-522 Zinc-finger double domain 510-533 C2H2-type zinc finger 511-533 C2H2-type zinc finger 511-533 Zinc finger, C2H2 type 526-550 Zinc-finger double domain 539-561 C2H2-type zinc finger 539-561 Zinc finger, C2H2 type 541-561 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MIKTQESLTLEDVAVEFSWEEWQLLDTAQKNLYRDVMVENYNHLVSLGYQTSKPDVLSKL 60 61 AHGQEPWTTDAKIQNKNCPGIGKVDSHLQEHSPNQRLLKSVQQCNGQNTLRNIVHLSKTH 120 121 FPIVQNHDTFDLYRKNLKSSLSLINQKRRHGINNPVEFIGGEKTLLHGKHERTHTKTRFS 180 181 ENAKCIHTKFQVFKHQRTQKIEKPHACIECEQTFLRKSQLIYHENICIQENPGSGQCEKL 240 241 SRSVLFTKHLKTNTTDKICIPNEYRKGSTVKSSLITHQQTHTEEKSYMCSECGKGFTMKR 300 301 YLIAHQRTHSGEKPYVCKECGKGFTVKSNLIVHQRTHTGEKPYICSECGKGFTMKRYLVV 360 361 HQRTHTGEKPYMCSECGKGFTVKSNLIVHQRSHTGEKSYICSECGKGFTVKRTLVIHQRT 420 421 HTGEKSYICNECGKGFTTKRTLIIHQRTHTGEKPYECNECGKAFSQKICLIQHERCHTGK 480 481 TPFVCTECGKSYSHKYGLITHQRIHTGEKPYECNECGKAFTTKSVLNVHQRTHTGERPYG 540 541 CSDCEKAFSHLSNLVKHKKMHTREMGRISQVENSCNGESQLLPYK |
| Interface Residues: | 272, 276, 297, 298, 300, 301, 303, 304, 306, 307, 310, 315, 325, 326, 327, 328, 329, 331, 332, 353, 354, 355, 356, 357, 360, 363, 364, 381, 382, 383, 384, 385, 386, 387, 388, 409, 410, 411, 412, 413, 416, 437, 438, 439, 440, 441, 444, 447, 466, 468, 469, 472, 478, 492, 493, 494, 495, 496, 497, 500, 501, 504, 521, 522, 523, 524, 525, 526, 527, 528, 529, 549, 550, 551, 552, 553, 555, 556 |
| 3D-footprint Homologues: | 7w1m_H, 1tf6_A, 6blw_A, 5yel_A, 2gli_A, 2jpa_A, 1ubd_C, 2kmk_A, 1tf3_A, 5ei9_F, 5k5i_A, 1llm_D, 2drp_D, 8ssq_A, 6u9q_A, 4x9j_A, 8ssu_A, 1f2i_J, 7y3m_I, 7ysf_A, 2lt7_A, 7y3l_A, 2wbs_A, 5v3j_F, 6e94_A, 5yj3_D, 5kkq_D, 7txc_E, 6ml4_A, 7n5w_A, 8cuc_F, 8gn3_A, 1g2f_F, 5kl3_A, 6jnm_A, 8h9h_G, 4m9v_C, 6a57_A, 3uk3_C, 5k5l_F |
| Binding Motifs: | UN0642.1 tkAGATCAAGym UN0642.2 tkAGATCAAG |
| Binding Sites: | UN0642.1.1 UN0642.1.10 / UN0642.1.11 UN0642.1.11 / UN0642.1.12 UN0642.1.12 / UN0642.1.13 UN0642.1.13 / UN0642.1.15 UN0642.1.14 / UN0642.1.16 UN0642.1.15 / UN0642.1.18 UN0642.1.16 / UN0642.1.19 UN0642.1.17 / UN0642.1.20 UN0642.1.18 UN0642.1.19 UN0642.1.2 UN0642.1.20 UN0642.1.3 UN0642.1.4 UN0642.1.5 UN0642.1.6 UN0642.1.7 UN0642.1.8 UN0642.1.10 / UN0642.1.9 UN0642.1.14 UN0642.1.17 UN0642.1.9 UN0642.2.1 UN0642.2.10 UN0642.2.11 UN0642.2.12 / UN0642.2.15 / UN0642.2.5 UN0642.2.13 UN0642.2.14 UN0642.2.16 / UN0642.2.6 UN0642.2.17 / UN0642.2.7 UN0642.2.18 UN0642.2.19 UN0642.2.2 UN0642.2.20 UN0642.2.3 UN0642.2.4 UN0642.2.8 UN0642.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.