Transcription Factor

Accessions: PBX2_MOUSE (HOCOMOCO 10)
Names: Homeobox protein PBX2, PBX2_MOUSE, Pre-B-cell leukemia transcription factor 2
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Length: 430
Pfam Domains: 50-243 PBC domain
245-304 Homeobox domain
263-301 Homeobox KN domain
Sequence:
(in bold interface residues)
1 MDERLLGPPPPGGGRGGLGLVGAEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI 60
61 MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN 120
121 MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE 180
181 QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR 240
241 FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI 300
301 RYKKNIGKFQEEANIYAVKTAVSVAQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP 360
361 GLNGDSYPASQVESLRHSMGPGSYGDNIGGGQIYSPREIRANGGWQEAVTPSSVTSPTEG 420
421 PGSVHSDTSN
Interface Residues: 212, 213, 214, 217, 218, 224, 228, 229, 245, 246, 247, 248, 249, 289, 290, 292, 293, 296, 297, 300, 301, 304
3D-footprint Homologues: 1au7_A, 8g87_X, 1e3o_C, 7xrc_C, 3cmy_A, 3d1n_M, 5zfz_A, 6fqp_B, 1puf_A, 1fjl_B, 2h1k_B, 1ig7_A, 6a8r_A, 6m3d_C, 2lkx_A, 1zq3_P, 1jgg_B, 3lnq_A, 2ld5_A, 2h8r_B, 5jlw_D, 4cyc_A, 2hdd_A, 7psx_B, 4j19_B, 2r5y_A, 2hos_A, 5zjt_E, 3a01_E, 1b72_A, 5hod_A, 3rkq_B, 1puf_B, 7q3o_C, 1le8_A, 1le8_B, 1du0_A, 6es3_K, 4xrs_G, 1mnm_C, 2d5v_B, 1k61_B, 5flv_I, 4qtr_D, 6fqq_E, 4xrm_B
Binding Motifs: PBX2_MOUSE.H10MO.C|M01284 krawkTGATTGAwkg
Related annotations: PaperBLAST

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