Transcription Factor

Accessions: T105892_1.02 (CISBP 1.02)
Names: hsf2, T105892_1.02;
Organisms: Danio rerio
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:HSF
Length: 489
Pfam Domains: 9-112 HSF-type DNA-binding
228-464 Vertebrate heat shock transcription factor
Sequence:
(in bold interface residues)
1 MKHSSNVPAFLTKLWTLVEDSDTNEFICWSQEGNSFLVLDEQRFAKEILPKFFKHNNMAS 60
61 FVRQLNMYGFRKVMHIDSGIVKQERDGPVEFQHPYFKHGQDDLLENIKRKVSNARPEESK 120
121 IRQDDLSKILTSVQSVHEQQENMDARLATLKRENEALWTELSDLRKVHVQQQQVIKELVQ 180
181 FIFTLVQNNRLLNLKRKRPLALNINGKKSKFIHQLFEEPIDHSKTTVNGLKNNSDISDDV 240
241 IICDITDEDPEVTDGISVPDEEDAEIVEITYESSPKTVRQDSANGTIVNSTAHQEAEPKT 300
301 TPDVSTTNSALQLNKPSCLSLEDPMKLMDSILSENGAISQNINLLGKVELMDYLDSIDCS 360
361 LEDFQAMLYGKQFNIDPDIIEETISETKNNNSKANKENLDSENTDKQLIQYTTCPLMAFL 420
421 DGCTPLTPSDPQPEDPPDLLDESLEMETPRSSLIRLEPLTEAEANEATLFYLCELNSDLP 480
481 NADTPPLDI
Interface Residues: 54, 55, 60, 62, 63, 64, 66, 67, 109
3D-footprint Homologues: 5hdn_C, 5d5w_B, 3hts_B, 5d5v_B, 7dci_A
Binding Motifs: M1249_1.02 gaawGTTCTATat
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.