Transcription Factor

Accessions: 6jgw_B (3D-footprint 20231221)
Names: CadR, Cd(II, Q93TP7_PSEPU
Organisms: Pseudomonas putida
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q93TP7
Length: 116
Pfam Domains: 1-68 MerR HTH family regulatory protein
2-39 MerR family regulatory protein
44-107 MerR, DNA binding
Sequence:
(in bold interface residues)
1 MKIGELAKATDCAVETIRYYEREQLLPEPARSDGNYRLYTQAHVERLTFIRNCRTLDMTL 60
61 DEIRSLLRLRDSPDDSGSVNALIDEHIEHVQARIDGLVALQEQLVELRRRCNAQGA
Interface Residues: 15, 18, 19, 22, 23, 36, 37
3D-footprint Homologues: 7tea_B, 5c8e_C, 6xh7_H, 2zhg_A, 7tec_A, 1r8d_B, 6xl5_H, 4r24_B, 6jgx_B, 1r8e_A, 7ckq_G, 4r4e_B, 6ldi_G, 2vz4_A, 5d8c_A
Binding Motifs: 6jgw_AB CnnTnTnGTnGCTnnAnnG
6jgw_B CnnTnTnGT
Binding Sites: 6jgw_C
6jgw_D
Publications: Liu X, Hu Q, Yang J, Huang S, Wei T, Chen W, He Y, Wang D, Liu Z, Wang K, Gan J, Chen H. Selective cadmium regulation mediated by a cooperative binding mechanism in CadR. Proc Natl Acad Sci U S A 116:20398-20403 (2019). [Pubmed]
Related annotations: PaperBLAST

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