Transcription Factor

Accessions: UP00112A (UniPROBE 20160601)
Names: goosecoid, Gsc, Homeobox protein goosecoid
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q02591
Description: goosecoid
Length: 93
Pfam Domains: 17-73 Homeobox domain
Sequence:
(in bold interface residues)
1 SRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKV 60
61 EVWFKNRRAKWRRQKRSSSEESESAEKWNKTSS
Interface Residues: 16, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 72, 73
3D-footprint Homologues: 4j19_B, 1puf_A, 2h1k_B, 1puf_B, 1fjl_B, 6a8r_A, 3cmy_A, 1ig7_A, 3d1n_M, 5zfz_A, 6fqp_B, 6m3d_C, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 1jgg_B, 2ld5_A, 7q3o_C, 6es3_K, 5flv_I, 5zjt_E, 3a01_E, 1au7_A, 5hod_A, 2hdd_A, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 7psx_B, 4cyc_A, 2d5v_B, 1e3o_C, 1le8_A, 7xrc_C, 2xsd_C, 3l1p_A, 4qtr_D, 6wig_A, 8g87_X, 1o4x_A, 1du0_A
Binding Motifs: UP00112A_1 aawmryTAATCCsytwv
Binding Sites: ACGGATTA
ACTAATCC
AGGATTAA
AGGATTAG
AGGGATTA
ATAATCCC
ATTAATCC
CCGGATTA
CCTAATCC
CGGATTAA
CGGATTAG
CTTAATCC
GATAATCC
GATTAATC
GCGGATTA
GCTAATCC
GGATTAAC
GGGATTAA
GGGGATTA
GGATTAGA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.