Transcription Factor

						

			
Accessions: T007532_1.02 (CISBP 1.02), Q9Z1N7 (JASPAR 2024)

			
Names: Arid3b, T007532_1.02;, ARI3B_MOUSE, ARID domain-containing protein 3B, AT-rich interactive domain-containing protein 3B, Bright and dead ringer protein, Bright-like protein
Organisms: Mus musculus
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: experiment type:PBM, family:ARID/BRIGHT
Length: 568
Pfam Domains:   213-301 ARID/BRIGHT DNA binding domain
Sequence: 
(in bold interface residues)		   1 MEPLQQQQQQQQQKQPQQPLLQMDAREKQGPQTRESQFLYASKLGTQPALLSITPGRPSG   60
  61 SSVLGPLARVPPATPVARMSEQSNVNSEPEEEEGGLEDEDGDDDVAEVAEKEAQAASKYF  120
 121 HMQKVTRQEPRATPMSSLLPVPGLSPQGQQTKEDHTKDASKAPPSVPTAGQPSWSLDEQL  180
 181 KQNGALAWSDDADGGRGREISRDFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIM  240
 241 AKQILDLYMLYKLVTEKGGLVEIINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYAY  300
 301 ECEKKALSSPAELQAAIDGNRREGRRPSYSSSLFGYSPAAAAAAAAAAAAAAASAASAGT  360
 361 PALLSSPKIRFSILGLGSSSGTSASSPRIPPASTLRKGDGVPVPVPNRLAVSGTLAGQQA  420
 421 GNRPGPLEHLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRINGRE  480
 481 DRAEPSAPALNLTTSNIGSINMSVDIDGTTYTGVLFAQKPVVHLIAGSTPQSIGSSASSS  540
 541 NSSSSHCSPSPTSSRGTPSAEPSTSWSL
Interface Residues: 270, 283, 284, 287, 288, 322, 431, 432, 436, 481, 482
3D-footprint Homologues: 2oeh_A, 1kqq_A, 1mse_C
Binding Motifs: M0104_1.02 awaTTAATwaa
MA0601.1 awaTTAATwaa
MA0601.2 waTTAAT
			
Publications: Herrscher R.F, Kaplan M.H, Lelsz D.L, Das C, Scheuermann R, Tucker P.W. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes & development 9:3067-82 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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