Transcription Factor

Accessions: 1h0m_B (3D-footprint 20231221)
Names: Transcriptional activator protein TraR, TRAR_RHIRD
Organisms: Agrobacterium tumefaciens, Rhizobium radiobacter (Agrobacterium tumefaciens)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P33905
Length: 230
Pfam Domains: 21-148 Autoinducer binding domain
168-224 Bacterial regulatory proteins, luxR family
Sequence:
(in bold interface residues)
1 MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQST 60
61 YFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKT 120
121 ANGFMSMFTMASDKPVIDIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRW 180
181 IAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
Interface Residues: 187, 198, 199, 200, 202, 203, 204, 206, 207
3D-footprint Homologues: 1l3l_A, 8dq1_C, 1pp7_U, 4wuh_B
Binding Motifs: 1h0m_AB TGcnnnnnngCA
1h0m_B gCAc
Binding Sites: 1h0m_E / 1h0m_F
Publications: Vannini A, Volpari C, Gargioli C, Muraglia E, Cortese R, De Francesco R, Neddermann P, Marco S.D. The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. The EMBO journal 21:4393-401 (2002). [Pubmed]
Related annotations: PaperBLAST

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