Transcription Factor

Accessions: 6gys_J (3D-footprint 20231221)
Names: CBF3B_YEAST, Centromere DNA-binding protein complex CBF3 subunit B, Centromere protein 3
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P40969
Length: 554
Pfam Domains: 1-34 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 HPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTITASSSKEYLPDLLLFWQNYEYWIT 60
61 NIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQKDQSFQLMNFAMENLGALYFGSIGDI 120
121 SELYLRVEQYWDRRADKNHSVDGKYWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLG 180
181 SNKRLNWEDGMQLVMCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLA 240
241 NSLLTQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPRKPIALH 300
301 TENSTEVLYWKIISLDRDLDQYLNKSSKPPLKTLDAIRRELDIFQYKVDSLEEDFRSNNS 360
361 RFQKFIALFQISTVSWKLFKMYLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRH 420
421 PMVMQTITRVVSFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSK 480
481 LKLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVPLNSDFRTIV 540
541 EEFQSEYNISDILS
Interface Residues: 9, 10, 11, 36, 38, 39, 332
3D-footprint Homologues: 1hwt_C, 6o19_A, 1pyi_A, 1zme_D, 1d66_B, 6gys_C
Binding Motifs: 6gys_ACEHJL CnnnnannnnnnnnngAnnT
Binding Sites: 6gys_F
6gys_G
Publications: Yan K, Zhang Z, Yang J, McLaughlin SH, Barford D. Architecture of the CBF3-centromere complex of the budding yeast kinetochore. Nat Struct Mol Biol 25:1103-1110 (2018). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.