Transcription Factor

Accessions: SOX3_MOUSE (HOCOMOCO 10), P53784 (JASPAR 2024)
Names: SOX3_MOUSE
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P53784
Length: 375
Pfam Domains: 68-129 Domain of unknown function (DUF1898)
69-137 HMG (high mobility group) box
138-231 SOX transcription factor
Sequence:
(in bold interface residues)
1 MYSLLETELKNPVGPPTPAAGTGVPAAPGAAGKSGANPAGGANAGNGGSGGANGGGGGGG 60
61 GGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 120
121 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPGAAAAAAAAAAAAAASSP 180
181 VGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPQMHRYDMAGLQYSP 240
241 MMPPGAQSYMNAAAAAAAASGYGGMAPSAAAAAAAAYGQQPATAAAAAAAAAAMSLGPMG 300
301 SVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQ 360
361 GAGTAVNGTVPLTHI
Interface Residues: 71, 74, 76, 77, 78, 80, 84, 95, 96, 97, 100, 138, 142, 185
3D-footprint Homologues: 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 1ckt_A, 1hry_A, 3tq6_B
Binding Motifs: MA0514.1 CCTTTGTyyy
SOX3_MOUSE.H10MO.C|M01347 kCCWTTGTbyy
MA0514.2 raACAATGgma
MA0514.3 ACAATGg
Binding Sites: MA0514.3.12
MA0514.1.1
MA0514.1.10
MA0514.1.11
MA0514.1.12
MA0514.1.13
MA0514.1.14
MA0514.1.15
MA0514.1.16
MA0514.1.17
MA0514.1.18
MA0514.1.19
MA0514.1.2
MA0514.1.20
MA0514.1.3
MA0514.1.4
MA0514.1.5
MA0514.1.6
MA0514.1.7
MA0514.1.8
MA0514.1.9
MA0514.2.1 / MA0514.2.2
MA0514.2.10 / MA0514.2.17
MA0514.2.11 / MA0514.2.18
MA0514.2.12
MA0514.2.13 / MA0514.2.20
MA0514.2.14
MA0514.2.15 / MA0514.2.16
MA0514.2.17
MA0514.2.18
MA0514.2.19
MA0514.2.2 / MA0514.2.5
MA0514.2.20
MA0514.2.3 / MA0514.2.6
MA0514.2.4 / MA0514.2.7
MA0514.2.5
MA0514.2.6 / MA0514.2.9
MA0514.2.11 / MA0514.2.7
MA0514.2.13 / MA0514.2.8
MA0514.2.16 / MA0514.2.9
MA0514.3.11 / MA0514.3.13 / MA0514.3.15 / MA0514.3.16 / MA0514.3.19 / MA0514.3.8
MA0514.3.1 / MA0514.3.10 / MA0514.3.4 / MA0514.3.6
MA0514.3.18 / MA0514.3.2 / MA0514.3.20 / MA0514.3.3
MA0514.3.17 / MA0514.3.9
MA0514.2.1
MA0514.2.10
MA0514.2.12
MA0514.2.14
MA0514.2.15
MA0514.2.19
MA0514.2.3
MA0514.2.4
MA0514.2.8
MA0514.3.14
MA0514.3.5
MA0514.3.7
Publications: Collignon J., Sockanathan S., Hacker A., Cohen-Tannoudji M., Norris D., Rastan S., Stevanovic M., Goodfellow P. N., Lovell-Badge R. A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. Development 122:509-520 (1996). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.