Transcription Factor

Accessions: UP00227A (UniPROBE 20160601)
Names: Duxl, Not Available, RIKEN cDNA 1110051B16 gene
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q3UY88
Description: RIKEN cDNA 1110051B16 gene
Length: 170
Pfam Domains: 14-69 Homeobox domain
94-148 Homeobox domain
Sequence:
(in bold interface residues)
1 ELSCXTGLLEKEARRRRIILTQSQKDTLRVWFEKNPNPDLATRGHLAKELGISESQIMTW 60
61 FQKHRKIRKQAEFACCSEESQEQEQDKPRVKEARRSRTHFTKFQTDILIEAFEKNRFPGI 120
121 VTREKLAQQTGIPESRIHIWFQNRRARHPDPGQNTQKTPHPPQSSQGPTQ
Interface Residues: 14, 15, 17, 53, 54, 55, 56, 58, 59, 62, 63, 65, 66, 70, 77, 80, 94, 95, 96, 97, 123, 135, 136, 138, 139, 142, 143, 146, 147
3D-footprint Homologues: 3d1n_M, 5zfz_A, 1nk2_P, 3l1p_A, 1au7_A, 2h8r_B, 8g87_X, 3cmy_A, 1ig7_A, 1puf_A, 2h1k_B, 1fjl_B, 6a8r_A, 2lkx_A, 1zq3_P, 1jgg_B, 6m3d_C, 3lnq_A, 7q3o_C, 6es3_K, 2ld5_A, 1b72_A, 3rkq_B, 4xrs_G, 2hdd_A, 4cyc_A, 2r5y_A, 2d5v_B, 5flv_I, 2hos_A, 1puf_B, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 1qpi_A, 5jlw_D, 1e3o_C, 1le8_A, 4xrm_B, 1du0_A, 4qtr_D
Binding Motifs: UP00227A_1 yrAccYAATCAAcgrws
Binding Sites: AATCAATC
ACTGATTG
ATCAATCA
ATTGATTA
ATTGATTG
CAATCAAA
CAATCAAC
CAATCAAG
CCAATCAA
CCAATCAG
CCCAATCA
CTAATCAA
CTCAATCA
CTGATTGA
GCAATCAA
GTTGATTA
TCAATCAA
TCCAATCA
TCTAATCA
TTAATCAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.