Transcription Factor

						

			
Accessions: T044530_1.02 (CISBP 1.02)

			
Names: T044530_1.02;, ZNF274
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:ChIP-seq, family:C2H2 ZF
Length: 652
Pfam Domains:     14-54 KRAB box
  156-245 SCAN domain
  286-326 KRAB box
  521-544 Zinc-finger double domain
  534-557 C2H2-type zinc finger
  534-556 Zinc finger, C2H2 type
  534-556 C2H2-type zinc finger
  548-572 Zinc-finger double domain
  562-584 C2H2-type zinc finger
  562-584 C2H2-type zinc finger
  562-584 Zinc finger, C2H2 type
  578-600 Zinc-finger double domain
  589-612 C2H2-type zinc finger
  590-612 C2H2-type zinc finger
  590-612 Zinc finger, C2H2 type
  604-629 Zinc-finger double domain
  618-641 C2H2-type zinc finger
  618-641 C2H2-type zinc finger
  618-640 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MASRLPTAWSCEPVTFEDVTLGFTPEEWGLLDLKQKSLYREVMLENYRNLVSVEHQLSKP   60
  61 DVVSQLEEAEDFWPVERGIPQDTIPEYPELQLDPKLDPLPAESPLMNIEVVEVLTLNQEV  120
 121 AGPRNAQIQALYAEDGSLSADAPSEQVQQQGKHPGDPEAARQRFRQFRYKDMTGPRELDQ  180
 181 LRELCHQWLQPKARSKEQILELLVLEQFLGALPVKLRTWVESQHPENCQEVVALVEGVTW  240
 241 MSEEEVLPAGQPAEGTTCCLEVTAQQEEKQEDAAICPVTVLPEEPVTFQDVAVDFSREEW  300
 301 GLLGPTQRTEYRDVMLETFGHLVSVGWETTLENKELAPNSDIPEEEPAPSLKVQESSRDC  360
 361 ALSSTLEDTLQGGVQEVQDTVLKQMESAQEKDLPQKKHFDNRESQANSGALDTNQVSLQK  420
 421 IDNPESQANSGALDTNQVLLHKIPPRKRLRKRDSQVKSMKHNSRVKIHQKSCERQKAKEG  480
 481 NGCRKTFSRSTKQITFIRIHKGSQVCRCSECGKIFRNPRYFSVHKKIHTGERPYVCQDCG  540
 541 KGFVQSSSLTQHQRVHSGERPFECQECGRTFNDRSAISQHLRTHTGAKPYKCQDCGKAFR  600
 601 QSSHLIRHQRTHTGERPYACNKCGKAFTQSSHLIGHQRTHNRTKRKKKQPTS
Interface Residues: 489, 491, 492, 495, 516, 517, 519, 520, 523, 525, 544, 545, 546, 547, 548, 550, 551, 552, 553, 554, 555, 557, 572, 573, 574, 575, 576, 577, 578, 579, 580, 583, 600, 601, 602, 603, 604, 605, 606, 607, 628, 629, 630, 631, 632, 634, 635, 638, 639
3D-footprint Homologues: 5v3j_F, 5yel_A, 7w1m_H, 3uk3_C, 5k5i_A, 6u9q_A, 1tf6_A, 1ubd_C, 6jnm_A, 2kmk_A, 6ml4_A, 8ssq_A, 6blw_A, 4x9j_A, 2gli_A, 8ssu_A, 1f2i_J, 5kkq_D, 5ei9_F, 1g2f_F, 4m9v_C, 7ysf_A, 6e94_A, 6a57_A, 2jpa_A, 1tf3_A, 7n5w_A, 5k5l_F, 8gn3_A, 5yj3_D, 5kl3_A, 8h9h_G, 2lt7_A, 8cuc_F, 7y3l_A, 1llm_D, 2drp_D, 2wbs_A, 7txc_E, 7y3m_I
Binding Motifs: M4551_1.02 yTCAyACTGGaGAGAAR
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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