Transcription Factor

						

			
Accessions: 4kdp_A (3D-footprint 20231221), 4kdp_B (3D-footprint 20231221)

			
Names: A0A0H2VJZ8_STAES, TcaR transcription regulator
Organisms: Staphylococcus epidermidis, strain ATCC 12228 / FDA PCI 1200
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8CN94
Length: 151
Pfam Domains:     34-93 MarR family
    37-93 MarR family
   37-103 Winged helix DNA-binding domain
    42-82 Bacterial regulatory protein, arsR family
Sequence: 
(in bold interface residues)		   1 MVRRIEDHISFLEKFINDVNTLTAKLLKDLQTEYGISAEQSHVLNMLSIEALTVGQITEK   60
  61 QGVNKAAVSRRVKKLLNAELVKLEKPDSNTDQRLKIIKLSNKGKKYIKERKAIMSHIASD  120
 121 MTSDFDSKEIEKVRQVLEIIDYRIQSYTSKL
Interface Residues: 37, 39, 43, 47, 64, 65, 66, 67, 69, 70, 71, 74, 93
3D-footprint Homologues: 4kdp_B, 7yho_A, 5yi2_J, 3q5f_A, 7dvv_A
Binding Motifs: 4kdp_AB CGCAGcGnnnA
4kdp_B CncAg
Binding Sites: 4kdp_H
			
Publications: Chang Y.M, Ho C.H, Chen C.K, Maestre-Reyna M, Chang-Chien M.W, Wang A.H. TcaR-ssDNA complex crystal structure reveals new DNA binding mechanism of the MarR family proteins. Nucleic acids research 42:5314-21 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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