Transcription Factor

Accessions: 5hlg_E (3D-footprint 20231221)
Names: MarR family transcriptional regulator, Q5HKZ1_STAEQ
Organisms: Staphylococcus epidermidis, strain ATCC 35984 / RP62A
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q5HKZ1
Length: 137
Pfam Domains: 32-89 Sugar-specific transcriptional regulator TrmB
36-94 MarR family
37-94 MarR family
37-103 Winged helix DNA-binding domain
42-110 HxlR-like helix-turn-helix
50-91 FeoC like transcriptional regulator
60-106 Transcriptional regulator PadR-like family
Sequence:
(in bold interface residues)
1 NMKQEQMRLANQLCFSAYNVSRLFAQFYEKKLKQFGITYSQYLVLLTLWEENPQTLNSIG 60
61 RHLDLSSNTLTPMLKRLEQSGWVKRERQQSDKRQLIITLTDNGQQQQEAVFEAISSCLDE 120
121 TKYVFEELEQTLKHLIE
Interface Residues: 57, 66, 67, 68, 69, 71, 72, 73, 75, 76, 93
3D-footprint Homologues: 7el3_B, 5yi2_J, 5h3r_A, 1z9c_A, 6c2s_C, 3q5f_A, 4lln_I, 7dvv_A, 4aik_A, 4fx4_B, 5hlg_E, 3zpl_B, 5f7q_C, 5hso_A, 6jbx_A
Binding Motifs: 5hlg_E CTnaATCGc
Binding Sites: 5hlg_M / 5hlg_N
Publications: Liu G, Liu X, Xu H, Liu X, Zhou H, Huang Z, Gan J, Chen H, Lan L, Yang CG. Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR. J Am Chem Soc 139:1598-1608 (2017). [Pubmed]
Related annotations: PaperBLAST

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