Transcription Factor

Accessions: Q94FL9 (JASPAR 2024), T21882 (AthalianaCistrome v4_May2016)
Names: MB3R4_ARATH, Myb-related protein 3R-4, Protein ENHANCED DEFECTIVE CYTOKINESIS, Transcription factor MYB3R-4, AT5G11510, MYB3R4, T21882;
Organisms: Arabidopsis thaliana
Libraries: JASPAR 2024 1, AthalianaCistrome v4_May2016 2
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Notes: ecotype:Col-0, experiment type: DAP-seq, family:MYB
Length: 961
Pfam Domains: 29-75 Myb-like DNA-binding domain
32-91 Myb-like DNA-binding domain
81-127 Myb-like DNA-binding domain
84-142 Myb-like DNA-binding domain
133-175 Myb-like DNA-binding domain
136-181 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MEAESSTPQERIPKLRHGRTSGPARRSTRGQWTAEEDEILRKAVHSFKGKNWKKIAEYFK 60
61 DRTDVQCLHRWQKVLNPELVKGPWTKEEDEMIVQLIEKYGPKKWSTIARFLPGRIGKQCR 120
121 ERWHNHLNPAINKEAWTQEEELLLIRAHQIYGNRWAELTKFLPGRSDNGIKNHWHSSVKK 180
181 KLDSYMSSGLLDQYQAMPLAPYERSSTLQSTFMQSNIDGNGCLNGQAENEIDSRQNSSMV 240
241 GCSLSARDFQNGTINIGHDFHPCGNSQENEQTAYHSEQFYYPELEDISVSISEVSYDMED 300
301 CSQFPDHNVSTSPSQDYQFDFQELSDISLEMRHNMSEIPMPYTKESKESTLGAPNSTLNI 360
361 DVATYTNSANVLTPETECCRVLFPDQESEGHSVSRSLTQEPNEFNQVDRRDPILYSSASD 420
421 RQISEATKSPTQSSSSRFTATAASGKGTLRPAPLIISPDKYSKKSSGLICHPFEVEPKCT 480
481 TNGNGSFICIGDPSSSTCVDEGTNNSSEEDQSYHVNDPKKLVPVNDFASLAEDRPHSLPK 540
541 HEPNMTNEQHHEDMGASSSLGFPSFDLPVFNCDLLQSKNDPLHDYSPLGIRKLLMSTMTC 600
601 MSPLRLWESPTGKKTLVGAQSILRKRTRDLLTPLSEKRSDKKLEIDIAASLAKDFSRLDV 660
661 MFDETENRQSNFGNSTGVIHGDRENHFHILNGDGEEWSGKPSSLFSHRMPEETMHIRKSL 720
721 EKVDQICMEANVREKDDSEQDVENVEFFSGILSEHNTGKPVLSTPGQSVTKAEKAQVSTP 780
781 RNQLQRTLMATSNKEHHSPSSVCLVINSPSRARNKEGHLVDNGTSNENFSIFCGTPFRRG 840
841 LESPSAWKSPFYINSLLPSPRFDTDLTIEDMGYIFSPGERSYESIGVMTQINEHTSAFAA 900
901 FADAMEVSISPTNDDARQKKELDKENNDPLLAERRVLDFNDCESPIKATEEVSSYLLKGC 960
961 R
Interface Residues: 29, 64, 65, 68, 69, 72, 73, 81, 115, 116, 117, 118, 120, 121, 125, 126, 167, 168, 171, 172, 175, 176, 177, 601, 612, 613, 616, 617, 620, 621, 624
3D-footprint Homologues: 7c4r_A, 1w0t_A, 5eyb_B, 7xur_A, 3osg_A, 1vfc_A, 2kdz_A, 1mse_C, 6kks_A, 3zqc_A, 5gzb_A
Binding Motifs: M0543 / MA1180.1 wwwwaTrrCCGTTrr
MA1180.2 wwaTrrCCGTTr
Binding Sites: MA1180.1.2
MA1180.1.17
MA1180.1.19
MA1180.1.12
MA1180.1.1 / MA1180.1.3
MA1180.1.18
MA1180.1.10
MA1180.1.8 / MA1180.1.9
MA1180.1.7
MA1180.1.5
MA1180.1.15
MA1180.1.11
MA1180.1.13
MA1180.1.14
MA1180.1.16
MA1180.1.20
MA1180.1.4
MA1180.1.6
MA1180.2.1 / MA1180.2.3
MA1180.2.10
MA1180.2.11
MA1180.2.12
MA1180.2.13
MA1180.2.14
MA1180.2.15
MA1180.2.16
MA1180.2.17
MA1180.2.18
MA1180.2.19
MA1180.2.2
MA1180.2.20
MA1180.2.4
MA1180.2.5
MA1180.2.6
MA1180.2.7
MA1180.2.8 / MA1180.2.9
Publications: Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.