Transcription Factor

						

			
Accessions: 5h3r_A (3D-footprint 20231221)

			
Names: MARR_ECOLI, Multiple antibiotic resistance protein MarR
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P27245
Length: 141
Pfam Domains:     33-92 MarR family
    35-93 MarR family
   35-101 Winged helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 TSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKV   60
  61 LSVDLGALTRMLDRLVSKGWVERLPNPNDKRGVLVKLTTGGAAICEQCHQLVGQDLHQEL  120
 121 TKNLTADEVATLEYLLKKVLP
Interface Residues: 50, 55, 64, 65, 66, 67, 69, 70, 74, 91
3D-footprint Homologues: 6qil_A, 7el3_B, 6c2s_C, 1z9c_A, 5h3r_A, 6jbx_A, 3q5f_A, 4aik_A, 5hlg_E, 3zpl_B, 5hso_A
Binding Motifs: 5h3r_A AnnTTGCC
5h3r_AB TnnTTGCCnGGGCAAnnT
Binding Sites: 5h3r_C
5h3r_D
			
Publications: Zhu R, Hao Z, Lou H, Song Y, Zhao J, Chen Y, Zhu J, Chen PR. Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator. J Biol Inorg Chem 22:685-693 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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