Transcription Factor
| Accessions: | UP00320A (UniPROBE 20160601) |
| Names: | Flocculation suppression protein, Sfl1, SFL1 protein, YOR140W, YOR3339W |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P20134 |
| Description: | Transcription repressor involved in regulation of flocculation-related genes, inhibits transcription by recruiting general corepressor Cyc8p-Tup1p to different promoters; negatively regulated by cA... |
| Length: | 300 |
| Pfam Domains: | 21-164 HSF-type DNA-binding |
| Sequence: (in bold interface residues) | 1 MVKKHGSKMLVGPRPPQNAIFIHKLYQILEDESLHDLIWWTPSGLSFMIKPVERFSKALA 60 61 TYFKHTNITSFVRQLNIYGFHKVSHDHSSNDANSGDDANTNDDSNTHDDNSGNKNSSGDE 120 121 NTGGGVQEKEKSNPTKIWEFKHSSGIFKKGDIEGLKHIKRRASSRNNSSINSRKNSSNQN 180 181 YDIDSGARVRPSSIQDPSTSSNSFGNFVPQIPGANNSIPEYFNNSHVTYENANHAPLESN 240 241 NPEMQEQNRPPNFQDETLKHLKEINFDMVKIIESMQHFISLQHSFCSQSFTFKNVSKKKS 300 |
| Interface Residues: | 64, 65, 70, 72, 73, 74, 76, 77, 152 |
| 3D-footprint Homologues: | 5hdn_C, 5d5v_B, 5d5w_B, 3hts_B, 7dci_A, 5cl8_A |
| Binding Motifs: | UP00320A_1 wmrmraAtmGAAGaaawawww |
| Binding Sites: | AAGAAGAA AATAGAAG AATCGAAG AGAAGAAA AGAAGAAG AGAAGGAA ATAGAAGA ATAGAAGC ATAGAAGG ATCGAAGA ATTTCTTC CGTAGAAG GAAGCTTC GAAGGAAA GGAAGAAA TAGAAGAA TGGAAGAA CGAAGAAA GCGAAGAA TCCTTCGA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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