Transcription Factor
| Accessions: | UP00250A (UniPROBE 20160601) |
| Names: | Homeodomain protein IRXB2, Iroquois homeobox protein 5, Iroquois related homeobox 5 (Drosophila), Iroquois-class homeodomain protein IRX-5, Irx5 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q9JKQ4 |
| Description: | Iroquois related homeobox 5 (Drosophila) |
| Length: | 96 |
| Pfam Domains: | 20-76 Homeobox domain 34-73 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 GYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTL 60 61 TQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEEN |
| Interface Residues: | 17, 19, 20, 23, 27, 61, 62, 64, 65, 68, 69, 70, 72, 73, 75, 76 |
| 3D-footprint Homologues: | 3d1n_M, 1jgg_B, 4cyc_A, 1ig7_A, 5jlw_D, 2r5y_A, 1puf_B, 2h1k_B, 2ld5_A, 7xrc_C, 3a01_E, 2d5v_B, 1k61_B, 5zjt_E, 1o4x_A, 1fjl_B, 5hod_A, 3cmy_A, 1le8_B, 6fqp_B, 4xrm_B, 2lkx_A, 1puf_A, 2hdd_A, 1mnm_C, 1b72_A, 6fqq_E, 4xrs_G, 5zfz_A, 3rkq_B, 1nk2_P, 1du0_A, 7psx_B, 5flv_I, 2hos_A |
| Binding Motifs: | UP00250A_1 wwwawACATGTwawwkw |
| Binding Sites: | AAACATGT AACATGTA AACATGTT ACAACATG ACATGTAA ACATGTAC ACATGTAG ACATGTAT ACATGTCA ACATGTTA ACATGTTC ACATGTTG ATCATGTA ATGTACAA ATGTACAT CATGTACA CTTGTACA GACATGTA GTACAAGA ATCTTGTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.