Transcription Factor

Accessions: T134688_1.02 (CISBP 1.02)
Names: nhr-66, T134688_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 659
Pfam Domains: 194-264 Zinc finger, C4 type (two domains)
397-597 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MTPQIGLTGLGSLTSLPPELLLQFARLDGFNLLPAVGSPAIPSSSSCSEPSTSQASTVVS 60
61 APTLPPPSPLTSLPQKPAPLMPSGHVTTVDQQNRQQHQQQQRQQQQAQQQNSMARKYSMD 120
121 TIQHHTMQHPHQLQYIPNHFMTASTDVFAAMDMSQKQSSPPGIFKIVAAKNEPSSSSNSQ 180
181 PGTPAMGDRRAVPACAICGTDSTGIHFGVDACAACSAFFRRTVVLNKDYSCNKGGKCTVV 240
241 KDGSAGQKCRACRFRKCISSGMDKNSVQHRRDAIGKYSAGVKRELSPDAEFEPSAKVSTV 300
301 SEPSTSSGPSGGFNQNVSSPAGIPRVPSTLRTTQASTCMNSACGQKSVLHELICRQNFLT 360
361 EQRQLFYAGCLGDWFRKPSSIENQTLSELTDFSSCMFHLWKIEPRLAADFMNRNRYLDPL 420
421 PIVEKLKIYRNFVIMRQSVEEPYLTWRHGGLEKRWFVMPNNTYIDFNNIAKYFENGALKD 480
481 LKLDYETTTNLFLPSFTHAMDTIGEKMKKNNITETELTILLGLVLLDPGIYGIHESTRKF 540
541 LKRIRDQLIHDVYMYYEDEMSHLYDPEIRMADIFMLVAAIKIHSIKTSENMHMLRVFDLI 600
601 PADACFNQMLDVESVNVSPDGQKDSEAEQGPSPVSVPEAARGSYQDDDMPPVLEKNCDL
Interface Residues: 203, 204, 206, 207, 213, 214, 216, 217, 220, 221, 247, 269, 271, 273, 276, 282, 284
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A
Binding Motifs: M1479_1.02 awwkTgTAgy
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.