Transcription Factor

Accessions: Q6QHK4 (JASPAR 2024)
Names: bHLHc8, Class C basic helix-loop-helix protein 8, Factor in the germline alpha, FIGalpha, FIGLA_HUMAN, Folliculogenesis-specific basic helix-loop-helix protein, Transcription factor FIGa
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q6QHK4
Length:
Binding Motifs: MA0820.1 wmCACCTGkw
MA1934.1 rcCGGAwrCAssTGky
MA1941.1 rsCGGAArCAGsTGgd
MA1945.1 rgmGGAArCAGGTGg
UN0529.1 rsmGGAwrCAssTGb
MA0820.2 CACCTG
MA1934.2 cCGGAwrCAssTG
MA1941.2 sCGGAArCAGsTG
MA1945.2 rgmGGAArCAGGTG
UN0529.2 smGGAwrCAssTG
Publications: Zhao H, Chen ZJ, Qin Y, Shi Y, Wang S, Choi Y, Simpson JL, Rajkovic A. Transcription factor FIGLA is mutated in patients with premature ovarian failure. Am J Hum Genet 82:1342-8 (2008). [Pubmed]

Guturu H, Doxey AC, Wenger AM, Bejerano G. Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements. Philos Trans R Soc Lond B Biol Sci 368:20130029 (2013). [Pubmed]

Ibarra IL, Hollmann NM, Klaus B, Augsten S, Velten B, Hennig J, Zaugg JB. Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions. Nat Commun 11:124 (2020). [Pubmed]
Related annotations: PaperBLAST

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