Transcription Factor

						

			
Accessions: ZNF167 (SMILE-seq 1.0)

			
Names: A7MAY2_HUMAN, Fragment, ZNF167, ZNF167 protein
Organisms: Homo sapiens
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: A7MAY2
Notes: TF family: KRAB+C2H4
Length: 754
Pfam Domains:    50-140 SCAN domain
  231-270 KRAB box
  372-393 Zinc-finger double domain
  383-405 C2H2-type zinc finger
  383-403 C2H2-type zinc finger
  383-405 Zinc finger, C2H2 type
  401-421 Zinc-finger double domain
  410-433 C2H2-type zinc finger
  411-433 C2H2-type zinc finger
  411-433 Zinc finger, C2H2 type
  428-450 Zinc-finger double domain
  438-462 C2H2-type zinc finger
  439-461 Zinc finger, C2H2 type
  439-461 C2H2-type zinc finger
  454-478 Zinc-finger double domain
  466-489 C2H2-type zinc finger
  467-489 Zinc finger, C2H2 type
  467-489 C2H2-type zinc finger
  482-504 Zinc-finger double domain
  495-517 Zinc finger, C2H2 type
  495-515 C2H2-type zinc finger
  509-532 Zinc-finger double domain
  522-543 C2H2-type zinc finger
  523-545 Zinc finger, C2H2 type
  538-562 Zinc-finger double domain
  550-573 C2H2-type zinc finger
  551-573 Zinc finger, C2H2 type
  551-573 C2H2-type zinc finger
  567-589 Zinc-finger double domain
  578-597 C2H2-type zinc finger
  579-601 C2H2-type zinc finger
  579-601 Zinc finger, C2H2 type
  596-616 Zinc-finger double domain
  607-629 C2H2-type zinc finger
  607-629 C2H2-type zinc finger
  607-629 Zinc finger, C2H2 type
  623-645 Zinc-finger double domain
  634-645 C2H2-type zinc finger
  635-657 C2H2-type zinc finger
  635-657 Zinc finger, C2H2 type
  650-674 Zinc-finger double domain
  662-685 C2H2-type zinc finger
  663-685 Zinc finger, C2H2 type
  663-685 C2H2-type zinc finger
  677-701 Zinc-finger double domain
  690-713 C2H2-type zinc finger
  691-713 Zinc finger, C2H2 type
  691-713 C2H2-type zinc finger
  708-729 Zinc-finger double domain
  718-741 C2H2-type zinc finger
  719-741 Zinc finger, C2H2 type
  719-741 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MTTAGRGNLGLIPRSTAFQKQEGRLTVKQEPANQTWGQGSSLQKNYPPVCEIFRLHFRQL   60
  61 CYHEMSGPQEALSRLRELCRWWLMPEVHTKEQILELLVLEQFLSILPGELRTWVQLHHPE  120
 121 SGEEAVAVVEDFQRHLSGSEEVSAPAQKQEMHFEETTALGTTKESPPTSPLSGGSAPGAH  180
 181 LEPPYDPGTHHLPSGDFAQCTSPVPTLPQVGNSGDQAGATVLRMVRPQDTVAYEDLSVDY  240
 241 TQKKWKSLTLSQRALQWNMMPENHHSMASLAGENMMKGSELTPKQEFFKGSESSNRTSGG  300
 301 LFGVVPGAAETGDVCEDTFKELEGQTSDEEGSRLENDFLEITDEDKKKSTKDRYDKYKEV  360
 361 GEHPPLSSSPVEHEGVLKGQKSYRCDECGKAFNRSSHLIGHQRIHTGEKPYECNECGKTF  420
 421 RQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPYKCNECAKAFTQSS  480
 481 RLTDHQRTHTGEKPYECNECGEAFIRSKSLARHQVLHTGKKPYKCNECGRAFCSNRNLID  540
 541 HQRIHTGEKPYECSECGKAFSRSKCLIRHQSLHTGEKPYKCSECGKAFNQNSQLIEHERI  600
 601 HTGEKPFECSECGKAFGLSKCLIRHQRLHTGEKPYKCNECGKSFNQNSHLIIHQRIHTGE  660
 661 KPYECNECGKVFSYSSSLMVHQRTHTGEKPYKCNDCGKAFSDSSQLIVHQRVHTGEKPYE  720
 721 CSECGKAFSQRSTFNHHQRTHTGEKSSGLAWSVS
Interface Residues: 393, 394, 396, 397, 400, 404, 421, 422, 424, 425, 428, 450, 451, 452, 453, 455, 456, 460, 477, 478, 479, 480, 481, 483, 484, 486, 487, 490, 506, 507, 508, 509, 511, 512, 533, 534, 535, 536, 537, 540, 544, 562, 563, 564, 565, 568, 572, 589, 590, 591, 592, 593, 596, 602, 616, 617, 618, 620, 621, 624, 628, 635, 645, 646, 647, 648, 649, 652, 655, 673, 674, 675, 676, 677, 678, 679, 680, 701, 702, 703, 704, 705, 707, 708, 709, 730, 731, 732, 733, 734, 736, 737
3D-footprint Homologues: 6jnm_A, 8ssq_A, 7w1m_H, 1f2i_J, 3uk3_C, 7ysf_A, 6ml4_A, 5v3j_F, 2drp_D, 5yj3_D, 2lt7_A, 6a57_A, 7n5w_A, 7txc_E, 1llm_D, 8h9h_G, 2jpa_A, 1ubd_C, 8ssu_A, 8gn3_A, 5kkq_D, 5yel_A, 1tf3_A, 1tf6_A, 5k5i_A, 2gli_A, 2kmk_A, 5ei9_F, 1g2f_F, 5kl3_A, 4x9j_A, 6e94_A, 8cuc_F, 7y3l_A, 6blw_A, 5k5l_F, 6u9q_A, 2wbs_A, 7y3m_I, 4m9v_C
Binding Motifs: ZNF167 ayAaACTgTarAGygcy
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.