Transcription Factor
| Accessions: | 1qpz_A (3D-footprint 20231221) |
| Names: | HTH-type transcriptional repressor PurR, Pur regulon repressor, PURINE NUCLEOTIDE SYNTHESIS REPRESSOR, PURR_ECOLI |
| Organisms: | Escherichia coli, strain K12 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P0ACP7 |
| Length: | 339 |
| Pfam Domains: | 2-47 Bacterial regulatory proteins, lacI family 59-324 Periplasmic binding proteins and sugar binding domain of LacI family 61-307 Periplasmic binding protein domain 170-330 Periplasmic binding protein-like domain |
| Sequence: (in bold interface residues) | 1 ATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKS 60 61 IGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLV 120 121 MCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREI 180 181 GVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPT 240 241 AVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETA 300 301 FNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYR |
| Interface Residues: | 3, 4, 13, 14, 15, 16, 18, 19, 25, 26, 27, 50, 53, 54 |
| 3D-footprint Homologues: | 1efa_B, 3oqm_C, 7ce1_D, 1l1m_B, 1zvv_A, 1jft_A |
| Binding Motifs: | 1qpz_A CGcanACg |
| Binding Sites: | 1qpz_M |
| Publications: | Glasfeld A, Koehler A.N, Schumacher M.A, Brennan R.G. The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions. Journal of molecular biology 291:347-61 (1999). [Pubmed] |
| Related annotations: | PaperBLAST |
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