Transcription Factor
| Accessions: | UP00146A (UniPROBE 20160601) |
| Names: | 2310038G18Rik, Brn5.0, C79593, class 6, Emb, Octamer-binding transcription factor EMB, POU domain, Pou6f1, transcription factor 1, Transcription regulatory protein MCP-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | POU domain, class 6, transcription factor 1 |
| Length: | 178 |
| Pfam Domains: | 17-90 Pou domain - N-terminal to homeobox domain 112-167 Homeobox domain |
| Sequence: (in bold interface residues) | 1 TVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQS 60 61 AICRFEKLDITPKSAQKLKPVLEKWLMEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTP 120 121 QAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP |
| Interface Residues: | 42, 43, 58, 59, 60, 61, 63, 64, 70, 74, 111, 112, 113, 114, 115, 117, 153, 154, 156, 157, 160, 161, 164, 165 |
| 3D-footprint Homologues: | 3l1p_A, 7u0g_M, 3d1n_M, 4cja_A, 1e3o_C, 1au7_A, 1o4x_A, 7xrc_C, 8g87_X, 2xsd_C, 4j19_B, 5zjt_E, 1fjl_B, 6a8r_A, 3cmy_A, 1puf_A, 1ig7_A, 5zfz_A, 1nk2_P, 1zq3_P, 2lkx_A, 2ld5_A, 6es3_K, 1mnm_C, 7q3o_C, 4xrs_G, 4cyc_A, 3a01_E, 5hod_A, 3lnq_A, 2h1k_B, 1b72_A, 5jlw_D, 3rkq_B, 2r5y_A, 2hdd_A, 1puf_B, 1jgg_B, 1le8_A, 1k61_B, 4qtr_D, 1du0_A |
| Binding Motifs: | UP00146A_1 vwmswTAATKAGstkgm UP00146A_2 rhasATAATGAGstkkc |
| Binding Sites: | ACTAATTA ACTCATTA ATAATTAG ATTAATTA CATAATGA CATAATTA CCTAATTA CCTCATTA CTAATGAG CTAATTAA CTAATTAG CTCATTAA CTCATTAC CTTAATTA GATAATGA GATAATTA GCTAATTA GCTCATTA TAATGAGA TATAATGA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.