Transcription Factor

Accessions: 5v0l_B (3D-footprint 20231221)
Names: Ah receptor, AHR_MOUSE, Aryl hydrocarbon receptor
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P30561
Length: 166
Pfam Domains: 3-41 Helix-loop-helix DNA-binding domain
60-125 PAS fold
Sequence:
(in bold interface residues)
1 RHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTQEGEFLL 60
61 QALVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALDQLP 120
121 PENASFMERCFRCDNSSGFLAMNFQGRLKYLHLPPQLALFAIATPL
Interface Residues: 2, 3, 29, 150, 152
3D-footprint Homologues: 5v0l_A, 1am9_A, 7f2f_B, 5nj8_C, 4h10_A, 7ssa_L, 5nj8_D, 4h10_B, 7d8t_A, 4zpk_A, 7xi3_A, 7xi3_B, 5v0l_B, 1a0a_B, 6g1l_A, 7xhv_B, 5sy7_B, 1a31_A
Binding Motifs: 5v0l_AB wcAGC
Binding Sites: 5v0l_C
5v0l_D
Publications: Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A 114:5431-5436 (2017). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.