Transcription Factor
Accessions: | 5v0l_B (3D-footprint 20231221) |
Names: | Ah receptor, AHR_MOUSE, Aryl hydrocarbon receptor |
Organisms: | Mus musculus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P30561 |
Length: | 166 |
Pfam Domains: | 3-41 Helix-loop-helix DNA-binding domain 60-125 PAS fold |
Sequence: (in bold interface residues) | 1 RHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTQEGEFLL 60 61 QALVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALDQLP 120 121 PENASFMERCFRCDNSSGFLAMNFQGRLKYLHLPPQLALFAIATPL |
Interface Residues: | 2, 3, 29, 150, 152 |
3D-footprint Homologues: | 5v0l_A, 1am9_A, 7f2f_B, 5nj8_C, 4h10_A, 7ssa_L, 5nj8_D, 4h10_B, 7d8t_A, 4zpk_A, 7xi3_A, 7xi3_B, 5v0l_B, 1a0a_B, 6g1l_A, 7xhv_B, 5sy7_B, 1a31_A |
Binding Motifs: | 5v0l_AB wcAGC |
Binding Sites: | 5v0l_C 5v0l_D |
Publications: | Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A 114:5431-5436 (2017). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.