Transcription Factor
Accessions: | P40427 (JASPAR 2024) |
Names: | Dpbx, EXD_DROME, Homeobox protein extradenticle |
Organisms: | Drosophila melanogaster |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 376 |
Pfam Domains: | 37-237 PBC domain 239-298 Homeobox domain 257-295 Homeobox KN domain |
Sequence: (in bold interface residues) | 1 MEDPNRMLAHTGGMMAPQGYGLSGQDDGQNAGSENEVRKQKDIGEILQQIMSISEQSLDE 60 61 AQARKHTLNCHRMKPALFSVLCEIKEKTVLSIRNTQEEEPPDPQLMRLDNMLIAEGVAGP 120 121 EKGGGGAAAASAAAASQGGSLSIDGADNAIEHSDYRAKLAQIRQIYHQELEKYEQACNEF 180 181 TTHVMNLLREQSRTRPITPKEIERMVQIIHKKFSSIQMQLKQSTCEAVMILRSRFLDARR 240 241 KRRNFSKQASEILNEYFYSHLSNPYPSEEAKEELARKCGITVSQVSNWFGNKRIRYKKNI 300 301 GKAQEEANLYAAKKAAGASPYSMAGPPSGTTTPMMSPAPPQDSMGYPMGSGGYDQQQPYD 360 361 NSMGGYDPNLHQDLSP |
Interface Residues: | 212, 218, 221, 222, 225, 239, 240, 241, 242, 243, 283, 284, 286, 287, 290, 291, 294, 295, 298 |
3D-footprint Homologues: | 1au7_A, 5zfz_A, 1fjl_B, 6a8r_A, 3d1n_M, 6fqp_B, 1puf_A, 3cmy_A, 2h1k_B, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 2ld5_A, 5jlw_D, 4cyc_A, 2r5y_A, 3l1p_A, 7psx_B, 1b72_A, 4j19_B, 3a01_E, 5zjt_E, 5hod_A, 1puf_B, 3rkq_B, 7q3o_C, 1le8_A, 4xrm_B, 2hdd_A, 1le8_B, 6m3d_C, 6es3_K, 4xrs_G, 1mnm_C, 2d5v_B, 1k61_B, 5flv_I, 1du0_A, 4qtr_D, 6fqq_E, 2hos_A |
Binding Motifs: | MA0222.1 tTTTGAYr MA0222.2 TTTGAYr |
Binding Sites: | MA0222.2.16 / MA0222.2.6 MA0222.2.15 / MA0222.2.7 MA0222.1.1 MA0222.1.10 MA0222.1.11 MA0222.1.12 MA0222.1.13 MA0222.1.14 MA0222.1.15 / MA0222.1.7 MA0222.1.16 MA0222.1.17 MA0222.1.18 MA0222.1.19 MA0222.1.2 MA0222.1.20 MA0222.1.3 MA0222.1.4 MA0222.1.5 MA0222.1.6 MA0222.1.8 MA0222.1.9 MA0222.2.1 MA0222.2.10 MA0222.2.11 MA0222.2.12 / MA0222.2.5 MA0222.2.13 MA0222.2.14 MA0222.2.17 MA0222.2.18 MA0222.2.19 MA0222.2.2 MA0222.2.20 MA0222.2.3 MA0222.2.4 MA0222.2.8 MA0222.2.9 |
Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.