Transcription Factor

						

			
Accessions: NFIL3_DBD (HumanTF 1.0)

			
Names: E4 promoter-binding protein 4, Interleukin-3 promoter transcriptional activator, Interleukin-3-binding protein 1, NFIL3, NFIL3_HUMAN, Nuclear factor interleukin-3-regulated protein, Transcriptional activator NF-IL3A
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q16649
Notes: Ensembl ID: ENSG00000165030; DNA-binding domain sequence; TF family: bZIP; Clone source: Gene synthesis
Length: 102
Pfam Domains:     18-69 Basic region leucine zipper
    25-69 bZIP transcription factor
   76-102 Vertebrate interleukin-3 regulated transcription factor
Sequence: 
(in bold interface residues)		   1 NKSSACRRKREFIPDEKKDAMYWEKRRKNNEAAKRSREKRRLNDLVLENKLIALGEENAT   60
  61 LKAELLSLKLKFGLISSTAYAQEIQKLSNSTAVYFQDYQTSK
Interface Residues: 26, 29, 30, 32, 33, 36, 37
3D-footprint Homologues: 6mg1_B, 8k86_A, 1dh3_C
Binding Motifs: NFIL3_DBD yrTTACrTAAym
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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