Transcription Factor

						

			
Accessions: Srebf1_DBD (HumanTF 1.0)

			
Names: SRBP1_MOUSE, Srebf1, SREBP-1, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1
Organisms: Mus musculus
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q9WTN3
Notes: Ensembl ID: ENSMUSG00000020538; DNA-binding domain sequence; TF family: bHLH; Clone source: Hughes lab.
Length: 86
Pfam Domains:     16-66 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 AAGSKALGSAQSRGEKRTAHNAIEKRYRSSINDKIVELKDLVVGTEAKLNKSAVLRKAID   60
  61 YIRFLQHSNQKLKQENLTLRSAHKSK
Interface Residues: 10, 17, 19, 20, 21, 23, 24, 27, 28, 49, 51
3D-footprint Homologues: 7lo5_D, 2ypa_A, 7z5k_B, 1an4_A, 7rcu_E, 8osl_O, 7d8t_A, 4zpk_A, 7ssa_L, 5nj8_D, 7f2f_B, 5eyo_A, 7xi3_A, 5v0l_A, 4h10_A, 5i50_B, 1am9_A, 6g1l_A, 4h10_B, 8osl_P, 5nj8_C
Binding Motifs: Srebf1_DBD rTCACGTGAy
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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