Transcription Factor

Accessions: Nr2f6_DBD (HumanTF 1.0)
Names: COUP transcription factor 3, COUP-TF3, EAR-2, Nr2f6, NR2F6_MOUSE, Nuclear receptor subfamily 2 group F member 6, V-erbA-related protein 2
Organisms: Mus musculus
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P43136
Notes: Ensembl ID: ENSMUSG00000002393; DNA-binding domain sequence; TF family: Nuclear_Receptor; Clone source: Hughes lab.
Length: 101
Pfam Domains: 19-87 Zinc finger, C4 type (two domains)
Sequence:
(in bold interface residues)
1 GATSDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRTIRRNLSYTCRSNR 60
61 DCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHALPG
Interface Residues: 28, 29, 31, 32, 38, 39, 41, 42, 45, 46, 70, 92, 94, 96
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A
Binding Motifs: Nr2f6_DBD_1 rAGGTCAArAGGTCA
Nr2f6_DBD_2 rRGGTCAAAGGTCA
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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