Transcription Factor

						

			
Accessions: P17014 (JASPAR 2024)

			
Names: GIOT-3, Gonadotropin-inducible ovary transcription repressor 3, Zinc finger protein 12, Zinc finger protein 325, Zinc finger protein KOX3, ZNF12_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P17014
Length: 697
Pfam Domains:      8-48 KRAB box
  255-278 Zinc-finger double domain
  268-291 C2H2-type zinc finger
  269-291 Zinc finger, C2H2 type
  287-306 Zinc-finger double domain
  296-307 C2H2-type zinc finger
  297-319 Zinc finger, C2H2 type
  297-319 C2H2-type zinc finger
  312-335 Zinc-finger double domain
  325-347 C2H2-type zinc finger
  325-347 Zinc finger, C2H2 type
  340-362 Zinc-finger double domain
  352-376 C2H2-type zinc finger
  353-375 C2H2-type zinc finger
  353-375 Zinc finger, C2H2 type
  367-391 Zinc-finger double domain
  381-403 C2H2-type zinc finger
  381-403 Zinc finger, C2H2 type
  381-401 C2H2-type zinc finger
  395-418 Zinc-finger double domain
  408-431 C2H2-type zinc finger
  409-431 C2H2-type zinc finger
  409-431 Zinc finger, C2H2 type
  424-447 Zinc-finger double domain
  436-459 C2H2-type zinc finger
  437-459 C2H2-type zinc finger
  437-459 Zinc finger, C2H2 type
  452-475 Zinc-finger double domain
  464-487 C2H2-type zinc finger
  465-487 C2H2-type zinc finger
  465-487 Zinc finger, C2H2 type
  479-503 Zinc-finger double domain
  492-506 C2H2-type zinc finger
  493-515 Zinc finger, C2H2 type
  493-515 C2H2-type zinc finger
  508-531 Zinc-finger double domain
  520-530 C2H2-type zinc finger
  521-543 Zinc finger, C2H2 type
  538-559 Zinc-finger double domain
  549-571 Zinc finger, C2H2 type
  564-586 Zinc-finger double domain
  576-599 C2H2-type zinc finger
  577-599 Zinc finger, C2H2 type
  577-599 C2H2-type zinc finger
  591-615 Zinc-finger double domain
  605-627 Zinc finger, C2H2 type
  620-644 Zinc-finger double domain
  633-655 C2H2-type zinc finger
  633-646 C2H2-type zinc finger
  633-655 Zinc finger, C2H2 type
  648-672 Zinc-finger double domain
  660-684 C2H2-type zinc finger
  661-683 C2H2-type zinc finger
  661-683 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MNKSLGPVSFKDVAVDFTQEEWQQLDPEQKITYRDVMLENYSNLVSVGYHIIKPDVISKL   60
  61 EQGEEPWIVEGEFLLQSYPDEVWQTDDLIERIQEEENKPSRQTVFIETLIEERGNVPGKT  120
 121 FDVETNPVPSRKIAYKNSLCDSCEKCLTSVSEYISSDGSYARMKADECSGCGKSLLHIKL  180
 181 EKTHPGDQAYEFNQNGEPYTLNEESLYQKIRILEKPFEYIECQKAFQKDTVFVNHMEEKP  240
 241 YKWNGSEIAFLQMSDLTVHQTSHMEMKPYECSECGKSFCKKSKFIIHQRTHTGEKPYECN  300
 301 QCGKSFCQKGTLTVHQRTHTGEKPYECNECGKNFYQKLHLIQHQRTHSGEKPYECSYCGK  360
 361 SFCQKTHLTQHQRTHSGERPYVCHDCGKTFSQKSALNDHQKIHTGVKLYKCSECGKCFCR  420
 421 KSTLTTHLRTHTGEKPYECNECGKFFSRLSYLTVHYRTHSGEKPYECNECGKTFYLNSAL  480
 481 MRHQRVHTGEKPYECNECGKLFSQLSYLTIHHRTHSGVKPYECSECGKTFYQNSALCRHR  540
 541 RIHKGEKPYECYICGKFFSQMSYLTIHHRIHSGEKPYECSECGKTFCQNSALNRHQRTHT  600
 601 GEKAYECYECGKCFSQMSYLTIHHRIHSGEKPFECNECGKAFSRMSYLTVHYRTHSGEKP  660
 661 YECTECGKKFYHKSAFNSHQRIHRRGNMNVIDVGRLL
Interface Residues: 252, 254, 258, 279, 280, 282, 283, 286, 308, 309, 310, 311, 314, 335, 336, 337, 338, 339, 342, 364, 365, 366, 367, 369, 370, 372, 373, 375, 376, 392, 393, 394, 395, 396, 397, 398, 399, 419, 420, 421, 422, 423, 424, 425, 426, 427, 429, 437, 447, 448, 449, 450, 451, 454, 458, 460, 474, 475, 476, 477, 478, 479, 481, 482, 485, 486, 503, 504, 505, 506, 507, 510, 531, 532, 534, 535, 538, 542, 559, 560, 562, 563, 566, 588, 590, 591, 593, 594, 616, 618, 619, 622, 638, 644, 645, 646, 647, 650, 672, 674, 675, 678
3D-footprint Homologues: 7w1m_H, 8cuc_F, 7y3l_A, 2gli_A, 5ei9_F, 5k5i_A, 5yel_A, 7txc_E, 5k5l_F, 8ssq_A, 8ssu_A, 6jnm_A, 5v3j_F, 6a57_A, 6u9q_A, 2jpa_A, 6dta_B, 1g2f_F, 4m9v_C, 7n5w_A, 1tf3_A, 1f2i_J, 1tf6_A, 6ml4_A, 8gn3_A, 8h9h_G, 7y3m_I, 2kmk_A, 6blw_A, 2wbs_A, 5kl3_A, 2drp_D, 7ysf_A, 5kkq_D, 5yj3_D, 3uk3_C, 6e94_A, 2lt7_A, 1ubd_C, 4x9j_A, 2p6r_A, 1llm_D
Binding Motifs: UN0161.1 GGksmTryTTGTTAymGCata
UN0161.2 GGksmTryTTGTTAymGCat
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.