Transcription Factor

Accessions: 1tf6_A (3D-footprint 20231221)
Names: S-TFIIIA/O-TFIIIA, TF3A_XENLA, TFIIIA, TRANSCRIPTION FACTOR IIIA
Organisms: Xenopus laevis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P03001
Length: 179
Pfam Domains: 4-28 C2H2-type zinc finger
21-47 Zinc-finger double domain
34-58 C2H2-type zinc finger
50-77 Zinc-finger double domain
64-89 Zinc finger, C2H2 type
64-89 C2H2-type zinc finger
96-120 Zinc finger, C2H2 type
96-120 C2H2-type zinc finger
113-138 Zinc-finger double domain
126-150 Zinc finger, C2H2 type
126-150 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 YKRYICSFADCGAAYNKNWKLQAHLCKHTGEKPFPCKEEGCEKGFTSLHHLTRHSLTHTG 60
61 EKNFTCDSDGCDLRFTTKANMKKHFNRFHNIKICVYVCHFENCGKAFKKHNQLKVHQFSH 120
121 TQQLPYECPHEGCDKRFSLPSRLKRHEKVHAGYPCKKDDSCSFVGKTWTLYLKHVAECH
Interface Residues: 15, 16, 17, 18, 19, 20, 22, 23, 29, 45, 46, 47, 48, 49, 50, 52, 53, 55, 56, 57, 59, 76, 77, 78, 79, 80, 83, 87, 99, 100, 101, 108, 109, 110, 111, 112, 113, 114, 115, 116, 138, 139, 140, 141, 142, 143, 144, 145, 146, 173
3D-footprint Homologues: 8gn3_A, 3uk3_C, 1tf3_A, 5v3j_F, 2gli_A, 1g2f_F, 5kkq_D, 1tf6_A, 4x9j_A, 5kl3_A, 1ubd_C, 7ysf_A, 6wmi_A, 5ei9_F, 5und_A, 1f2i_J, 5k5i_A, 8ssu_A, 2lt7_A, 2i13_A, 7w1m_H, 7n5w_A, 8cuc_F, 7y3l_A, 6ml4_A, 6blw_A, 1llm_D, 7txc_E, 2wbs_A, 5yj3_D, 8ssq_A, 1mey_C, 2drp_D, 8h9h_G, 7eyi_G, 7y3m_I, 6e94_A, 2jpa_A, 5yel_A, 6jnm_A, 6u9q_A, 2kmk_A, 4m9v_C, 6a57_A
Binding Motifs: 1tf6_A TGGTnannnnnnkGATGGGAAACC
Binding Sites: 1tf6_B
1tf6_C
Publications: Nolte R.T, Conlin R.M, Harrison S.C, Brown R.S. Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex. Proceedings of the National Academy of Sciences of the United States of America 95:2938-43 (1998). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.