Transcription Factor

						

			
Accessions: Q9UL17 (JASPAR 2024)

			
Names: T-box protein 21, T-box transcription factor TBX21, T-cell-specific T-box transcription factor T-bet, TBX21_HUMAN, Transcription factor TBLYM
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9UL17
Length: 535
Pfam Domains:   139-327 T-box
Sequence: 
(in bold interface residues)		   1 MGIVEPGCGDMLTGTEPMPGSDEGRAPGADPQHRYFYPEPGAQDADERRGGGSLGSPYPG   60
  61 GALVPAPPSRFLGAYAYPPRPQAAGFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYPG  120
 121 PREDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPT  180
 181 SHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFG  240
 241 KLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVNDGEPEAACNASNTHIFTFQETQFI  300
 301 AVTAYQNAEITQLKIDNNPFAKGFRENFESMYTSVDTSIPSPPGPNCQFLGGDHYSPLLP  360
 361 NQYPVPSRFYPDLPGQAKDVVPQAYWLGAPRDHSYEAEFRAVSMKPAFLPSAPGPTMSYY  420
 421 RGQEVLAPGAGWPVAPQYPPKMGPASWFRPMRTLPMEPGPGGSEGRGPEDQGPPLVWTEI  480
 481 APIRPESSDSGLGEGDSKRRRVSPYPSSGDSSSPAGAPSPFDKEAEGQFYNYFPN
Interface Residues: 164, 303, 304, 320, 324
3D-footprint Homologues: 1xbr_B
Binding Motifs: MA0690.1 aAGGTGTGAA
UN0485.1 AGGTGytAATwa
UN0488.1 tCACACCyrATa
UN0508.1 TmaCACCGGAAr
UN0550.1 aGGTGtsrTGcGGGyk
UN0555.1 aGGTGTcrwGsGGGy
UN0564.1 ragGTGyTAATkr
UN0566.1 TmrCACyTmATWAA
UN0574.1 aGGTGTGACsGTTr
UN0576.1 AGGTGyGAArGGATTA
MA0690.2 tTTCACACCTt
MA0690.3 TTCACACCTt
UN0488.2 tCACACCyrAT
UN0550.2 aGGTGtsrTGcGGG
UN0555.2 aGGTGTcrwGsGGG
UN0564.2 agGTGyTAATk
			
Publications: Naiche LA, Harrelson Z, Kelly RG, Papaioannou VE. T-box genes in vertebrate development. Annu Rev Genet : (2005;39:219-39.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.