Transcription Factor
| Accessions: | Q8NDQ6 (JASPAR 2024) |
| Names: | ZN540_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8NDQ6 |
| Length: | 660 |
| Pfam Domains: | 6-46 KRAB box 187-198 C2H2-type zinc finger 188-209 C2H2-type zinc finger 202-226 Zinc-finger double domain 216-237 C2H2-type zinc finger 216-237 Zinc finger, C2H2 type 216-237 C2H2-type zinc finger 230-253 Zinc-finger double domain 242-263 C2H2-type zinc finger 243-265 Zinc finger, C2H2 type 243-265 C2H2-type zinc finger 258-280 Zinc-finger double domain 271-293 C2H2-type zinc finger 273-291 C2H2-type zinc finger 286-308 Zinc-finger double domain 299-309 C2H2-type zinc finger 314-337 Zinc-finger double domain 326-337 C2H2-type zinc finger 327-349 Zinc finger, C2H2 type 327-349 C2H2-type zinc finger 342-364 Zinc-finger double domain 354-377 C2H2-type zinc finger 355-377 Zinc finger, C2H2 type 355-377 C2H2-type zinc finger 370-392 Zinc-finger double domain 382-393 C2H2-type zinc finger 383-405 Zinc finger, C2H2 type 383-403 C2H2-type zinc finger 398-422 Zinc-finger double domain 411-431 C2H2-type zinc finger 411-433 Zinc finger, C2H2 type 411-431 C2H2-type zinc finger 425-448 Zinc-finger double domain 438-461 C2H2-type zinc finger 439-461 Zinc finger, C2H2 type 454-476 Zinc-finger double domain 466-477 C2H2-type zinc finger 467-489 Zinc finger, C2H2 type 485-504 Zinc-finger double domain 495-511 C2H2-type zinc finger 495-517 Zinc finger, C2H2 type 510-532 Zinc-finger double domain 522-532 C2H2-type zinc finger 523-545 C2H2-type zinc finger 523-545 Zinc finger, C2H2 type 537-562 Zinc-finger double domain 551-573 C2H2-type zinc finger 551-571 C2H2-type zinc finger 551-573 Zinc finger, C2H2 type 566-590 Zinc-finger double domain 578-599 C2H2-type zinc finger 579-601 C2H2-type zinc finger 579-601 Zinc finger, C2H2 type 593-616 Zinc-finger double domain 606-617 C2H2-type zinc finger 607-629 C2H2-type zinc finger 607-629 Zinc finger, C2H2 type 621-645 Zinc-finger double domain 634-657 C2H2-type zinc finger 635-658 C2H2-type zinc finger 635-657 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAHALVTFRDVAIDFSQKEWECLDTTQRKLYRDVMLENYNNLVSLGYSGSKPDVITLLEQ 60 61 GKEPCVVARDVTGRQCPGLLSRHKTKKLSSEKDIHEISLSKESIIEKSKTLRLKGSIFRN 120 121 EWQNKSEFEGQQGLKERSISQKKIVSKKMSTDRKRPSFTLNQRIHNSEKSCDSHLVQHGK 180 181 IDSDVKHDCKECGSTFNNVYQLTLHQKIHTGEKSCKCEKCGKVFSHSYQLTLHQRFHTGE 240 241 KPYECQECGKTFTLYPQLNRHQKIHTGKKPYMCKKCDKGFFSRLELTQHKRIHTGKKSYE 300 301 CKECGKVFQLIFYFKEHERIHTGKKPYECKECGKAFSVCGQLTRHQKIHTGVKPYECKEC 360 361 GKTFRLSFYLTEHRRTHAGKKPYECKECGKSFNVRGQLNRHKTIHTGIKPFACKVCEKAF 420 421 SYSGDLRVHSRIHTGEKPYECKECGKAFMLRSVLTEHQRLHTGVKPYECKECGKTFRVRS 480 481 QISLHKKIHTDVKPYKCVRCGKTFRFGFYLTEHQRIHTGEKPYKCKECGKAFIRRGNLKE 540 541 HLKIHSGLKPYDCKECGKSFSRRGQFTEHQKIHTGVKPYKCKECGKAFSRSVDLRIHQRI 600 601 HTGEKPYECKQCGKAFRLNSHLTEHQRIHTGEKPYECKVCRKAFRQYSHLYQHQKTHNVI 660 |
| Interface Residues: | 226, 228, 229, 254, 256, 257, 260, 281, 282, 284, 285, 288, 291, 292, 310, 311, 312, 313, 315, 316, 320, 338, 339, 340, 341, 343, 344, 366, 367, 368, 369, 372, 393, 394, 395, 396, 397, 400, 421, 422, 423, 424, 425, 427, 428, 431, 450, 451, 452, 453, 456, 457, 460, 462, 476, 477, 478, 479, 480, 481, 482, 484, 485, 488, 505, 506, 507, 508, 509, 510, 511, 512, 533, 534, 535, 536, 537, 539, 540, 542, 543, 546, 551, 561, 562, 563, 564, 565, 568, 572, 589, 590, 591, 592, 593, 596, 617, 618, 619, 620, 621, 624, 645, 646, 647, 648, 649, 651, 652, 655 |
| 3D-footprint Homologues: | 1tf6_A, 7w1m_H, 6a57_A, 6jnm_A, 8ssq_A, 5und_A, 2lt7_A, 5k5i_A, 6e94_A, 5kl3_A, 1g2f_F, 5yel_A, 5k5l_F, 8ssu_A, 6ml4_A, 5v3j_F, 4m9v_C, 6wmi_A, 2i13_A, 3uk3_C, 8cuc_F, 7y3l_A, 7txc_E, 2drp_D, 5yj3_D, 8gn3_A, 6blw_A, 2jpa_A, 2kmk_A, 7n5w_A, 5ei9_F, 1mey_C, 2gli_A, 1llm_D, 5kkq_D, 2wbs_A, 8h9h_G, 7eyi_G, 7ysf_A, 1ubd_C, 1tf3_A, 1f2i_J, 4x9j_A, 6u9q_A, 7y3m_I |
| Binding Motifs: | UN0627.1 rhAAACGTCCAC UN0627.2 AAACGTCCAC |
| Binding Sites: | UN0627.1.1 UN0627.1.10 / UN0627.1.15 / UN0627.1.20 UN0627.1.11 / UN0627.1.16 UN0627.1.12 UN0627.1.13 UN0627.1.14 / UN0627.1.17 UN0627.1.15 UN0627.1.16 UN0627.1.18 UN0627.1.19 UN0627.1.2 / UN0627.1.3 UN0627.1.3 / UN0627.1.4 UN0627.1.4 / UN0627.1.6 UN0627.1.5 / UN0627.1.8 UN0627.1.6 / UN0627.1.9 UN0627.1.11 / UN0627.1.7 UN0627.1.12 / UN0627.1.8 UN0627.1.14 / UN0627.1.9 UN0627.1.10 UN0627.1.13 UN0627.1.17 UN0627.1.18 UN0627.1.19 UN0627.1.2 UN0627.1.20 UN0627.1.5 UN0627.1.7 UN0627.2.1 UN0627.2.10 / UN0627.2.14 / UN0627.2.17 / UN0627.2.18 / UN0627.2.19 / UN0627.2.20 UN0627.2.11 UN0627.2.12 UN0627.2.13 UN0627.2.15 UN0627.2.16 UN0627.2.2 / UN0627.2.8 / UN0627.2.9 UN0627.2.3 UN0627.2.4 UN0627.2.5 UN0627.2.6 UN0627.2.7 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.