Transcription Factor

						

			
Accessions: Q8N782 (JASPAR 2024)

			
Names: ZN525_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8N782
Length: 197
Pfam Domains:      3-28 Zinc-finger double domain
    16-37 C2H2-type zinc finger
    17-39 Zinc finger, C2H2 type
    17-39 C2H2-type zinc finger
    31-55 Zinc-finger double domain
    44-55 C2H2-type zinc finger
    45-67 Zinc finger, C2H2 type
    45-64 C2H2-type zinc finger
    60-83 Zinc-finger double domain
    72-95 C2H2-type zinc finger
    73-95 Zinc finger, C2H2 type
    73-95 C2H2-type zinc finger
   87-112 Zinc-finger double domain
  100-123 C2H2-type zinc finger
  101-123 C2H2-type zinc finger
  101-123 Zinc finger, C2H2 type
  116-138 Zinc-finger double domain
  128-149 C2H2-type zinc finger
  129-151 C2H2-type zinc finger
  129-151 Zinc finger, C2H2 type
  143-167 Zinc-finger double domain
  156-173 C2H2-type zinc finger
  157-179 C2H2-type zinc finger
  157-179 Zinc finger, C2H2 type
  171-195 Zinc-finger double domain
Sequence: 
(in bold interface residues)		   1 MSSLTYHHRLHTGEKPYKCEECDKAFRHNSALQRHRRIHTGEKPHKCNECGKTFSQKSYL   60
  61 ACHRSIHTGKKPYECEECDKAFSFKSNLESHRITHTGEKPYKCNDCGKTFSHMSTLTCHR  120
 121 RLHTGEKPYKCEECDEAFRFKSSLERHRRIHNGEKLYKCNECGKTFSQELSLTCHCRLHS  180
 181 GEKPCKCGECDKAYSFK
Interface Residues: 6, 10, 27, 28, 30, 31, 33, 34, 36, 37, 40, 55, 56, 57, 58, 59, 61, 62, 83, 84, 85, 86, 87, 90, 92, 93, 111, 112, 113, 114, 115, 117, 118, 139, 140, 141, 142, 143, 146, 168, 169, 170, 171, 174, 196, 197
3D-footprint Homologues: 8ssu_A, 8ssq_A, 1tf3_A, 8gn3_A, 2gli_A, 5v3j_F, 1tf6_A, 7w1m_H, 7y3m_I, 6e94_A, 2jpa_A, 1ubd_C, 7y3l_A, 8cuc_F, 2kmk_A, 2lt7_A, 7n5w_A, 8h9h_G, 7ysf_A, 7txc_E, 6u9q_A, 2drp_D
Binding Motifs: UN0201.1 AAATTGCTAATGAAGT
Binding Sites: UN0201.1.1
UN0201.1.10 / UN0201.1.11
UN0201.1.11
UN0201.1.12 / UN0201.1.13
UN0201.1.13 / UN0201.1.15
UN0201.1.14
UN0201.1.15
UN0201.1.16
UN0201.1.17
UN0201.1.18
UN0201.1.19
UN0201.1.2
UN0201.1.20
UN0201.1.3 / UN0201.1.4
UN0201.1.4 / UN0201.1.5
UN0201.1.5 / UN0201.1.6
UN0201.1.6 / UN0201.1.7
UN0201.1.7 / UN0201.1.8
UN0201.1.8
UN0201.1.10 / UN0201.1.9
UN0201.1.12
UN0201.1.14
UN0201.1.18
UN0201.1.19
UN0201.1.20
UN0201.1.3
UN0201.1.9
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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