Transcription Factor

Accessions: UBP1 (HT-SELEX2 May2017)
Names: ENSG00000153560, UBP1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: CP2 experiment: HT-SELEX Hamming distance: 2 cycle: 4, TF family: CP2 experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 4
Length: 265
Pfam Domains: 39-243 CP2 transcription factor
Sequence:
(in bold interface residues)
1 VHDFDASLSGIGQELGAGAYSMSDVLALPIFKQEDSSLPLDGETEHPPFQYVMCAATSPA 60
61 VKLHDETLTYLNQGQSYEIRMLDNRKMGDMPEINGKLVKSIIRVVFHDRRLQYTEHQQLE 120
121 GWKWNRPGDRLLDLDIPMSVGIIDTRTNPSQLNAVEFLWDPAKRTSAFIQVHCISTEFTP 180
181 RKHGGEKGVPFRIQVDTFKQNENGEYTDHLHSASCQIKVFKPKGADRKQKTDREKMEKRT 240
241 AHEKEKYQPSYDTTILTEMRLEPII
Interface Residues: 222, 227, 230
3D-footprint Homologues: 5mpf_B
Binding Motifs: UBP1_2 arCCrGytyraaCyrGyt
UBP1_methyl_1 awCyrGttyraaCyrGwt
Related annotations: PaperBLAST

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