Transcription Factor
Accessions: | 5c8e_B (3D-footprint 20231221) |
Names: | Light-dependent transcriptional regulator CarH, Q746J7_THET2 |
Organisms: | strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q746J7 |
Length: | 276 |
Pfam Domains: | 3-71 MerR HTH family regulatory protein 4-41 MerR family regulatory protein 80-152 B12 binding domain |
Sequence: (in bold interface residues) | 1 GVYTIAEVEAMTGLSAEVLRQWERRYGFPKPRRTPGGHRLYSAEDVEALKTIKRWLEEGA 60 61 TPKAAIRRYLAQEVRPEDLGTGLLEALLRGDLAGAEALFRRGLRFWGPEGVLEHLLLPVL 120 121 REVGEAWHRGEIGVAEEHLASTFLRARLQELLDLAGFPPGPPVLVTTPPGERHEIGAMLA 180 181 AYHLRRKGVPALYLGPDTPLPDLRALARRLGAGAVVLSAVLSEPLRALPDGALKDLAPRV 240 241 FLGGQGAGPEEARRLGAEYMEDLKGLAEALWLPRGP |
Interface Residues: | 17, 20, 21, 24, 25, 38 |
3D-footprint Homologues: | 7tec_A, 5c8e_C, 6ldi_G, 1r8d_B, 5d8c_A, 6xh7_H, 4r24_B, 5i44_I, 7tea_B, 4r4e_B, 6jgx_B |
Binding Motifs: | 5c8e_BC TACAnnnnnnTGACA |
Publications: | Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, ElÃas-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed] |
Related annotations: | PaperBLAST |
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