Transcription Factor
| Accessions: | T154001_1.02 (CISBP 1.02), O04336 (JASPAR 2024), T07963 (AthalianaCistrome v4_May2016) |
| Names: | T154001_1.02;, WRKY21, Probable WRKY transcription factor 21, WRK21_ARATH, WRKY DNA-binding protein 21, AT2G30590, T07963; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq |
| Length: | 380 |
| Pfam Domains: | 264-310 Plant zinc cluster domain 314-372 WRKY DNA -binding domain |
| Sequence: (in bold interface residues) | 1 MEEIEGTNRAAVESCHRVLNLLHRSQQQDHVGFEKNLVSETREAVIRFKRVGSLLSSSVG 60 61 HARFRRAKKLQSHVSQSLLLDPCQQRTTEVPSSSSQKTPVLRSGFQELSLRQPSDSLTLG 120 121 TRSFSLNSNAKAPLLQLNQQTMPPSNYPTLFPVQQQQQQQQQQQQQEQQQQQQQQQQQFH 180 181 ERLQAHHLHQQQQLQKHQAELMLRKCNGGISLSFDNSSCTPTMSSTRSFVSSLSIDGSVA 240 241 NIEGKNSFHFGVPSSTDQNSLHSKRKCPLKGDEHGSLKCGSSSRCHCAKKRKHRVRRSIR 300 301 VPAISNKVADIPPDDYSWRKYGQKPIKGSPYPRGYYKCSSMRGCPARKHVERCLEDPAML 360 361 IVTYEAEHNHPKLPSQAITT |
| Interface Residues: | 320, 321, 323, 324, 335 |
| 3D-footprint Homologues: | 7z0u_A |
| Binding Motifs: | M1686_1.02 awrGTCAAcg MA1079.1 awrGTCAAcg M0827 aAAAGTCAACg M0834 rkcGTTGACTTTt MA1079.2 wwwaAAAGTCAACgmhwwww MA1079.3 aAAAGTCAACg |
| Binding Sites: | MA1079.1.8 MA1079.1.12 MA1079.1.1 MA1079.1.10 MA1079.1.11 MA1079.1.13 MA1079.1.14 MA1079.1.15 MA1079.1.16 MA1079.1.17 MA1079.1.18 MA1079.1.19 MA1079.1.2 MA1079.1.20 MA1079.1.3 MA1079.1.4 MA1079.1.5 MA1079.1.6 MA1079.1.7 MA1079.1.9 MA1079.2.1 MA1079.2.10 MA1079.2.11 MA1079.2.12 MA1079.2.13 MA1079.2.14 MA1079.2.15 MA1079.2.16 MA1079.2.17 MA1079.2.18 MA1079.2.19 MA1079.2.2 MA1079.2.20 MA1079.2.3 MA1079.2.4 MA1079.2.5 MA1079.2.6 MA1079.2.7 MA1079.2.8 MA1079.2.9 MA1079.3.1 / MA1079.3.15 MA1079.3.10 MA1079.3.11 MA1079.3.12 / MA1079.3.18 / MA1079.3.19 MA1079.3.13 MA1079.3.14 MA1079.3.16 / MA1079.3.17 MA1079.3.2 MA1079.3.20 MA1079.3.3 / MA1079.3.8 MA1079.3.4 MA1079.3.5 MA1079.3.6 MA1079.3.7 MA1079.3.9 |
| Publications: | Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.