Transcription Factor

						

			
Accessions: YY1_full (HumanTF 1.0)

			
Names: Delta transcription factor, INO80 complex subunit S, NF-E1, Transcriptional repressor protein YY1, TYY1_HUMAN, Yin and yang 1, YY-1, YY1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P25490
Notes: Ensembl ID: ENSG00000100811; Full protein sequence; TF family: znfC2H2; Clone source: Megaman
Length: 415
Pfam Domains:   297-320 C2H2-type zinc finger
  325-347 C2H2-type zinc finger
  325-347 Zinc finger, C2H2 type
  340-365 Zinc-finger double domain
  353-377 Zinc finger, C2H2 type
  353-377 C2H2-type zinc finger
  369-395 Zinc-finger double domain
  383-407 Zinc finger, C2H2 type
  383-407 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MASGDTLYIATDGSEMPAEIVELHEIEVETIPVETIETTVVGEEEEEDDDDEDGGGGDHG   60
  61 GGGGHGHAGHHHHHHHHHHHPPMIALQPLVTDDPTQVHHHQEVILVQTREEVVGGDDSDG  120
 121 LRAEDGFEDQILIPVPAPAGGDDDYIEQTLVTVAAAGKSGGGGSSSSGGGRVKKGGGKKS  180
 181 GKKSYLSGGAGAAGGGGADPGNKKWEQKQVQIKTLEGEFSVTMWSSDEKKDIDHETVVEE  240
 241 QIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDAPRTIACPH  300
 301 KGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGC  360
 361 GKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ*
Interface Residues: 308, 309, 310, 311, 312, 314, 315, 316, 317, 318, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 347, 361, 364, 365, 366, 367, 368, 369, 371, 372, 376, 393, 395, 396, 397, 398, 399, 400, 401, 402
3D-footprint Homologues: 7w1m_H, 5ei9_F, 6ml4_A, 8gn3_A, 4m9v_C, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 8ssq_A, 8ssu_A, 5kkq_D, 8cuc_F, 7y3l_A, 1tf3_A, 7n5w_A, 6jnm_A, 7txc_E, 2kmk_A, 6blw_A, 2gli_A, 4x9j_A, 5kl3_A, 1tf6_A, 8h9h_G, 2lt7_A, 7y3m_I, 6a57_A, 4gnx_Z, 5k5i_A, 3uk3_C, 1g2f_F, 5v3j_F, 1llm_D, 6u9q_A, 5yel_A, 2wbs_A, 5yj3_D, 1f2i_J
Binding Motifs: YY1_full dccgCCATtay
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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