Transcription Factor
| Accessions: | Q8TCN5 (JASPAR 2024) |
| Names: | ZN507_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8TCN5 |
| Length: | 953 |
| Pfam Domains: | 125-147 C2H2-type zinc-finger domain 125-147 C2H2-type zinc finger 641-663 C2H2-type zinc finger 658-675 Zinc-finger double domain 669-691 C2H2-type zinc finger 697-720 C2H2-type zinc finger 697-720 Zinc finger, C2H2 type 758-780 C2H2-type zinc-finger domain 774-797 Zinc-finger double domain 786-808 C2H2-type zinc finger 911-933 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MEESSSVAMLVPDIGEQEAILTAESIISPSLEIDEQRKTKPDPLIHVIQKLSKIVENEKS 60 61 QKCLLIGKKRPRSSAATHSLETQELCEIPAKVIQSPAADTRRAEMSQTNFTPDTLAQNEG 120 121 KAMSYQCSLCKFLSSSFSVLKDHIKQHGQQNEVILMCSECHITSRSQEELEAHVVNDHDN 180 181 DANIHTQSKAQQCVSPSSSLCRKTTERNETIPDIPVSVDNLQTHTVQTASVAEMGRRKWY 240 241 AYEQYGMYRCLFCSYTCGQQRMLKTHAWKHAGEVDCSYPIFENENEPLGLLDSSAAAAPG 300 301 GVDAVVIAIGESELSIHNGPSVQVQICSSEQLSSSSPLEQSAERGVHLSQSVTLDPNEEE 360 361 MLEVISDAEENLIPDSLLTSAQKIISSSPNKKGHVNVIVERLPSAEETLSQKRFLMNTEM 420 421 EEGKDLSLTEAQIGREGMDDVYRADKCTVDIGGLIIGWSSSEKKDELMNKGLATDENAPP 480 481 GRRRTNSESLRLHSLAAEALVTMPIRAAELTRANLGHYGDINLLDPDTSQRQVDSTLAAY 540 541 SKMMSPLKNSSDGLTSLNQSNSTLVALPEGRQELSDGQVKTGISMSLLTVIEKLRERTDQ 600 601 NASDDDILKELQDNAQCQPNSDTSLSGNNVVEYIPNAERPYRCRLCHYTSGNKGYIKQHL 660 661 RVHRQRQPYQCPICEHIADNSKDLESHMIHHCKTRIYQCKQCEESFHYKSQLRNHEREQH 720 721 SLPDTLSIATSNEPRISSDTADGKCVQEGNKSSVQKQYRCDVCDYTSTTYVGVRNHRRIH 780 781 NSDKPYRCSLCGYVCSHPPSLKSHMWKHASDQNYNYEQVNKAINDAISQSGRVLGKSPGK 840 841 TQLKSSEESADPVTGSSENAVSSSELMSQTPSEVLGTNENEKLSPTSNTSYSLEKISSLA 900 901 PPSMEYCVLLFCCCICGFESTSKENLLDHMKEHEGEIVNIILNKDHNTALNTN |
| Interface Residues: | 589, 590, 592, 595, 599, 624, 626, 628, 629, 631, 632, 633, 641, 647, 648, 649, 650, 651, 652, 653, 654, 655, 657, 658, 659, 660, 661, 664, 679, 680, 681, 682, 683, 684, 685, 686, 687, 690, 707, 708, 709, 710, 711, 712, 713, 714, 715, 716, 717, 719, 739, 741, 742, 745, 747, 748, 751, 753, 766, 767, 768, 769, 770, 771, 772, 774, 775, 779, 797, 798, 799, 800, 802, 803, 807, 825, 826 |
| 3D-footprint Homologues: | 7w1m_H, 8ssu_A, 2lt7_A, 5kkq_D, 2kmk_A, 2drp_D, 7n5w_A, 5kl3_A, 7ysf_A, 6wmi_A, 5k5i_A, 1mey_C, 5und_A, 1f2i_J, 7eyi_G, 5v3j_F, 4x9j_A, 1g2f_F, 5ei9_F, 8h9h_G, 4m9v_C, 6e94_A, 8ssq_A, 6jnm_A, 6a57_A, 2i13_A, 6blw_A, 2jpa_A, 1llm_D, 7txc_E, 1yuj_A, 5k5l_F, 8gn3_A, 2wbs_A, 5yel_A, 1tf6_A, 1ubd_C, 6ml4_A, 3uk3_C, 8cuc_F, 7y3l_A, 7y3m_I, 6u9q_A, 5yj3_D |
| Binding Motifs: | UN0624.1 rrTCACrTGAcym UN0624.2 rTCACrTGAc |
| Binding Sites: | UN0624.1.1 / UN0624.1.2 UN0624.1.10 UN0624.1.11 UN0624.1.12 UN0624.1.13 UN0624.1.14 UN0624.1.15 UN0624.1.16 UN0624.1.17 UN0624.1.18 UN0624.1.19 UN0624.1.2 / UN0624.1.4 UN0624.1.20 UN0624.1.3 / UN0624.1.7 UN0624.1.4 / UN0624.1.9 UN0624.1.10 / UN0624.1.5 UN0624.1.13 / UN0624.1.6 UN0624.1.15 / UN0624.1.7 UN0624.1.18 / UN0624.1.8 UN0624.1.19 / UN0624.1.9 UN0624.2.13 / UN0624.2.18 UN0624.2.12 / UN0624.2.19 UN0624.2.14 UN0624.2.11 UN0624.2.5 / UN0624.2.7 UN0624.1.1 UN0624.1.11 UN0624.1.12 UN0624.1.14 UN0624.1.16 UN0624.1.17 UN0624.1.20 UN0624.1.3 UN0624.1.5 UN0624.1.6 UN0624.1.8 UN0624.2.1 UN0624.2.10 / UN0624.2.6 UN0624.2.15 UN0624.2.16 UN0624.2.17 UN0624.2.2 UN0624.2.20 UN0624.2.3 UN0624.2.4 UN0624.2.8 UN0624.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.