Transcription Factor
| Accessions: | STAT6_HUMAN (HOCOMOCO 10) |
| Names: | IL-4 Stat, Signal transducer and activator of transcription 6, STAT6_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Uniprot: | P42226 |
| Length: | 847 |
| Pfam Domains: | 2-115 STAT protein, protein interaction domain 125-271 STAT protein, all-alpha domain 273-527 STAT protein, DNA binding domain 538-616 SH2 domain |
| Sequence: (in bold interface residues) | 1 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT 60 61 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP 120 121 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA 180 181 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ 240 241 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR 300 301 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF 360 361 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN 420 421 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK 480 481 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG 540 541 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR 600 601 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE 660 661 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE 720 721 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF 780 781 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD 840 841 LRANPSW |
| Interface Residues: | 284, 377, 414, 415, 416, 417, 418 |
| 3D-footprint Homologues: | 1bf5_A, 1bg1_A, 4y5w_B |
| Binding Motifs: | STAT6_HUMAN.H10MO.C|M01544 TTCyyaGGAAwyt |
| Related annotations: | PaperBLAST |
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