Transcription Factor

						

			
Accessions: FOXA1_MOUSE (HOCOMOCO 10)

			
Names: Forkhead box protein A1, FOXA1_MOUSE, Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Length: 468
Pfam Domains:    17-169 Forkhead N-terminal region
  170-265 Fork head domain
  393-457 HNF3 C-terminal domain
Sequence: 
(in bold interface residues)		   1 MLGTVKMEGHESNDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMT   60
  61 PASFNMSYANTGLGAGLSPGAVAGMPGASAGAMNSMTAAGVTAMGTALSPGGMGSMGAQP  120
 121 ATSMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLIT  180
 181 MAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGK  240
 241 GSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGSGGGGSKGGPESRKDPSGPGNPS  300
 301 AESPLHRGVHGKASQLEGAPAPGPAASPQTLDHSGATATGGASELKSPASSSAPPISSGP  360
 361 GALASVPPSHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQAL  420
 421 QYSPYGATLPASLPLGSASVATRSPIEPSALEPAYYQGVYSRPVLNTS
Interface Residues: 160, 162, 164, 165, 167, 213, 215, 216, 217, 219, 220, 221, 223, 224, 233, 240, 265
3D-footprint Homologues: 7yz7_A, 7yzb_A, 7vox_H, 2hdc_A, 3g73_A, 6el8_A, 7tdx_A, 3l2c_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3qrf_G
Binding Motifs: FOXA1_MOUSE.H10MO.B|M01094 TGTTTrCwywk
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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