Transcription Factor

						

			
Accessions: T077991_1.02 (CISBP 1.02)

			
Names: ETS1, T077991_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Ets
Length: 485
Pfam Domains:    98-179 Sterile alpha motif (SAM)/Pointed domain
  379-460 Ets-domain
Sequence: 
(in bold interface residues)		   1 MSYFVDSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNCGFQSNYHQQRPCYPFWDEMATQ   60
  61 EVPTGLEHCVSDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETH  120
 121 VRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKED  180
 181 VKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEEL  240
 241 LSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIE  300
 301 SYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNK  360
 361 DKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWG  420
 421 KRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK  480
 481 PDADE
Interface Residues: 376, 431, 432, 434, 435, 436, 438, 439, 453
3D-footprint Homologues: 3zp5_A, 7jsa_J, 3jtg_A, 1dux_F, 8ee9_F, 4mhg_A, 8smh_F, 4uno_A, 2stt_A, 8smj_F, 4lg0_B, 1yo5_C, 4iri_A, 1awc_A, 4l18_B, 1bc8_C
Binding Motifs: M3049_1.02 aCmGGAwryv
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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