Transcription Factor

						

			
Accessions: HSF2_DBD (HumanTF 1.0)

			
Names: Heat shock factor protein 2, Heat shock transcription factor 2, HSF 2, HSF2, HSF2_HUMAN, HSTF 2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q03933
Notes: Ensembl ID: ENSG00000025156; DNA-binding domain sequence; TF family: HSF; Clone source: MGC
Length: 218
Pfam Domains:     9-113 HSF-type DNA-binding
Sequence: 
(in bold interface residues)		   1 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS   60
  61 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK  120
 121 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ  180
 181 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVK
Interface Residues: 54, 55, 60, 62, 63, 64, 66, 67, 109
3D-footprint Homologues: 5hdn_C, 5d5v_B, 5d5w_B, 3hts_B, 7dci_A
Binding Motifs: HSF2_DBD TTCTAGAAyrTTC
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.