Transcription Factor
| Accessions: | P09067 (JASPAR 2024) |
| Names: | Homeobox protein HHO.C10, Homeobox protein Hox-2A, Homeobox protein Hox-B5, Homeobox protein Hu-1, HXB5_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 269 |
| Pfam Domains: | 195-251 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS 60 61 ASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQ 120 121 ATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWM 180 181 RKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKI 240 241 WFQNRRMKWKKDNKLKSMSLATAGSAFQP |
| Interface Residues: | 178, 195, 196, 197, 198, 236, 237, 239, 240, 243, 244, 246, 247, 248, 251 |
| 3D-footprint Homologues: | 5zfz_A, 3cmy_A, 8ejp_B, 6a8r_A, 1puf_A, 8pmf_A, 1fjl_B, 1zq3_P, 2lkx_A, 1jgg_B, 3lnq_A, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 1nk2_P, 5flv_I, 3a01_E, 9b8u_A, 1ig7_A, 5zjt_E, 4cyc_A, 8ik5_C, 7psx_B, 5hod_A, 2hdd_A, 2r5y_A, 8osb_E, 5jlw_D, 2hos_A, 8eml_B, 4xrs_G, 1puf_B, 3rkq_B, 1b72_A, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 8bx1_A, 1o4x_A, 1du0_A, 4qtr_D, 8g87_X |
| Binding Motifs: | MA0904.2 sTMATKAs MA0904.3 TMATKA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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