Transcription Factor

						

			
Accessions: NFE2 (HT-SELEX2 May2017)

			
Names: ENSG00000123405, NFE2
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: bZIP experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: bZIP experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2
Length: 148
Pfam Domains:    37-127 bZIP Maf transcription factor
   67-109 bZIP transcription factor
   69-107 Basic region leucine zipper
Sequence: 
(in bold interface residues)		   1 LALEPSSGPVRAKPTARGEAGSRDERRALAMKIPFPTDKIVNLPVDDFNELLARYPLTES   60
  61 QLALVRDIRRRGKNKVAAQNCRKRKLETIVQLERELERLTNERERLLRARGEADRTLEVM  120
 121 RQQLTELYRDIFQHLRDESGNSYSPEEY
Interface Residues: 70, 74, 75, 77, 78, 81, 82, 85
3D-footprint Homologues: 2wt7_B, 7x5e_E, 4eot_A, 7x5e_F, 1skn_P, 2wt7_A, 5vpe_D, 5t01_B
Binding Motifs: NFE2_2 sRTGAsTCAYs
NFE2_methyl_1 sATGAsTCATs
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.