Transcription Factor

Accessions: 6w1a_A (3D-footprint 20231221)
Names: A0A0J9X288_STRDY, Transcriptional regulator
Organisms: Streptococcus dysgalactiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A0A0J9
Length: 274
Pfam Domains: 4-63 Helix-turn-helix domain
7-60 Helix-turn-helix
Sequence:
(in bold interface residues)
1 KELGKTLRRLRQGKQVSISSLADEHLSKSQISRFERGESEISCSRLLNLLDKLNITIDEF 60
61 VSTHSKTHTHFFTLLSRVRKYYAEKNVAKLLKLLEDYAHKDYESTMIKAILSSIEPTVEP 120
121 SEEEVTRLTDYLFSVEQWGYYEIILLGNCSRFINYNTLFLLTKEMVTSFAYSEQNKTNKT 180
181 LVTQLSINCLIISIDYSYFDHSHYLIEKIEFLLRDELNFYEKTVFLYVHGYYKLKQGQVS 240
241 GKDDMRQALQIFKYLGEDALYYSYKEHYRKEVLG
Interface Residues: 9, 19, 20, 21, 22, 27, 28, 29, 30, 32, 33, 36, 38, 39
3D-footprint Homologues: 2r1j_L, 6w1f_A, 3u3w_B, 6w1a_A
Binding Motifs: 6w1a_A CcCa
6w1a_AB CcCasywdcACa
Binding Sites: 6w1a_E
6w1a_F
Publications: Capodagli GC, Tylor KM, Kaelber JT, Petrou VI, Federle MJ, Neiditch MB. Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. Proc Natl Acad Sci U S A 117:24494-24502 (2020). [Pubmed]
Related annotations: PaperBLAST

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