Transcription Factor
| Accessions: | UP00346A (UniPROBE 20160601) |
| Names: | DAS1, Meiosis-specific transcription factor NDT80, Ndt80, YHR124W |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P38830 |
| Description: | Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containin... |
| Length: | 627 |
| Pfam Domains: | 105-333 NDT80 / PhoG like DNA-binding family |
| Sequence: (in bold interface residues) | 1 MNEMENTDPVLQDDLVSKYERELSTEQEEDTPVILTQLNEDGTTSNYFDKRKLKIAPRST 60 61 LQFKVGPPFELVRDYCPVVESHTGRTLDLRIIPRIDRGFDHIDEEWVGYKRNYFTLVSTF 120 121 ETANCDLDTFLKSSFDLLVEDSSVESRLRVQYFAIKIKAKNDDDDTEINLVQHTAKRDKG 180 181 PQFCPSVCPLVPSPLPKHQIIREASNVRNITKMKKYDSTFYLHRDHVNYEEYGVDSLLFS 240 241 YPEDSIQKVARYERVQFASSISVKKPSQQNKHFSLHVILGAVVDPDTFHGENPGIPYDEL 300 301 ALKNGSKGMFVYLQEMKTPPLIIRGRSPSNYASSQRITVRTPSSVNSSQNSTKRKMPSMA 360 361 QPSNESCLNARPSKRRSKVALGAPNSGASISPIKSRQSTPMEASKENEDPFFRPNKRVET 420 421 LEHIQNKLGALKNQCPDSSLKYPSSSSRGMEGCLEKEDLVYSSSFSVNMKQIELKPARSF 480 481 EHENIFKVGSLAFKKINELPHENYDITIEKKSMEQNYLRPEIGSRSECKTSYGNELSLSN 540 541 ISFSILPNSAENFHLETALFPATEEDVPRTFSRILETGSFQNYYQKMDAENADRVYSKGV 600 601 KLIASGTLPSGIFNREELFEEDSFYKY |
| Interface Residues: | 57, 58, 111, 112, 177, 178, 326 |
| 3D-footprint Homologues: | 1mnn_A |
| Binding Motifs: | UP00346A_1 hytcckgmCACAAAAacsvaa |
| Binding Sites: | AACACAAA ACACAAAA ACCACAAA ACTTTGTG ATTTGTGG ATTTTGTG CACAAAAA CACAAAAC CACAAAAG CACAAAGA CCACAAAA CCACAAAG GACACAAA GCCACAAA GTCACAAA TACACAAA TCACAAAA TCCACAAA GCACAAAA GTACAAAA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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