Transcription Factor

Accessions: T131314_1.02 (CISBP 1.02)
Names: Cbr-nhr-134, T131314_1.02;
Organisms: Caenorhabditis briggsae
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 378
Pfam Domains: 10-77 Zinc finger, C4 type (two domains)
176-377 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MPAPLFLSGPCEICGQQTTGRHFGVMSCRACAAFFRRAAGWDRQRTECPKGNCPIFADGK 60
61 FQCKKCRLQRCLDVGMDASKFQSNRDLISCSNKFIKRVALFIGPSQSLSTFLGRPMFILC 120
121 CEPDRASHIKTFIDVQHLVDIANKMFHQEPTMNGRPYQYHNSLEKLSVTLDDMRLKQPDK 180
181 RITQMTKIGKDESIFVWEQAFLRAVEWFANFPEFNELEDFIKLEIMKASWICWTRLEKLT 240
241 ETAEYQRRRIFSNTVYMLGNDTCLDFENYEIDLTWCTNYTLEQLEFYMSPAVEQNCQGCV 300
301 QNLVNLAPTSIEVNYMLLQVSLYHAGKKCQGKVLEACEKLMQTQADHLHDYYVNKMKQPN 360
361 YSARLAKMMKINKGLKRI
Interface Residues: 19, 20, 22, 23, 29, 30, 32, 33, 36, 37, 61, 81, 84, 85, 88, 91
3D-footprint Homologues: 6fbq_A, 7wnh_D, 6l6q_B, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A
Binding Motifs: M1428_1.02 kTGTGwCy
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.