Transcription Factor

						

			
Accessions: P20824 (JASPAR 2024)

			
Names: NUC1_NEUCR
Organisms: Neurospora crassa
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P20824
Length: 801
Pfam Domains:   646-736 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MNSSSWSAPDHSHHPALHTAADDDFHQYLDINDMGDLSDALDFDFRDFGADHHTAPHAGR   60
  61 HAADHLLHPSGGEHLDTPMTGTDMSMILSPVDHAMLRHGVQQQQHHQQQQHQQHQMPTIT  120
 121 TTAPYQNAPTALIQPSTPSEAIVNTIDAQIQFLQQQKLHAQHQQLQEQQAAFFASQQNHI  180
 181 VPPTPQSLELTAGSSQNYYAQSTLSDQHHSGPQKQQQPQQAIDYRYTRIKDQHDMSFTPL  240
 241 VSPAVTPLETHFPIDTPFAVPGAYFSPLTSPALHAQNDALGIIDQRLGMMSGSSPREMEL  300
 301 EPPAMSQASVSPGDLARKTRKNAVKARAKSGSGIKQSPISKPIRRKTATTPMLNPQALNQ  360
 361 LVENAAPSQERQQPLTPLIPTSSSSTAGVTDSENGSISPENLNDVVLPVEMPPPPLPKPR  420
 421 SAKPSPFLAPQASGSAVPINLQPGRPGIASPATPASLMKLSSPSNRNPSVVGTGSHDPMD  480
 481 PDHIENFELPDSINFSSAPKPAPIITTLGTPALDPLQKAAAPLQTPGLPPPPSPAVAKPL  540
 541 ALPSAALSSPQLKPDSAHSLKRTPQLAPMGRSSKKRASVTSIQMSPALRPKISPSIKPLL  600
 601 PGGSAGAEDAASILLATKSNYQRILEGNTVPGVSYPSELSTNLTSKRTSHKIAEQGRRNR  660
 661 INSALQEIATLLPKAPAKEGGDGDGDGHSSSGGGGGSGGADREDKREKDKDKAGGGIPNS  720
 721 KASTVEMAIEYIKQLQKEVADANKRAEEAERKLVEMKMQGGAATGSGSSVGDAGDLGTPT  780
 781 TEANPVVDEDLKSGGGDAMDE
Interface Residues: 647, 650, 651, 653, 654, 657, 658
3D-footprint Homologues: 1a0a_B, 4h10_A, 7ssa_L, 4h10_B, 8ia3_B, 6g1l_A, 8osl_O, 7d8t_A, 8osl_P
Binding Motifs: MA1436.1 mCACGTGm
MA1436.2 mCACGTG
			
Publications: Peleg Y, Metzenberg RL. Analysis of the DNA-binding and dimerization activities of Neurospora crassa transcription factor NUC-1. Mol Cell Biol 14:7816-26 (1994). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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