Transcription Factor

						

			
Accessions: Q9Y3M9 (JASPAR 2024)

			
Names: ZN337_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9Y3M9
Length: 751
Pfam Domains:     13-52 KRAB box
  207-230 C2H2-type zinc finger
  208-230 Zinc finger, C2H2 type
  223-246 Zinc-finger double domain
  236-258 C2H2-type zinc finger
  236-259 C2H2-type zinc finger
  236-258 Zinc finger, C2H2 type
  250-274 Zinc-finger double domain
  264-286 C2H2-type zinc finger
  266-286 Zinc finger, C2H2 type
  279-302 Zinc-finger double domain
  291-315 C2H2-type zinc finger
  292-314 C2H2-type zinc finger
  292-314 Zinc finger, C2H2 type
  306-331 Zinc-finger double domain
  320-342 Zinc finger, C2H2 type
  336-359 Zinc-finger double domain
  348-370 Zinc finger, C2H2 type
  348-371 C2H2-type zinc finger
  348-370 C2H2-type zinc finger
  363-386 Zinc-finger double domain
  376-398 Zinc finger, C2H2 type
  376-386 C2H2-type zinc finger
  376-398 C2H2-type zinc finger
  390-414 Zinc-finger double domain
  404-426 Zinc finger, C2H2 type
  404-427 C2H2-type zinc finger
  404-426 C2H2-type zinc finger
  419-441 Zinc-finger double domain
  432-454 Zinc finger, C2H2 type
  432-454 C2H2-type zinc finger
  447-469 Zinc-finger double domain
  460-482 Zinc finger, C2H2 type
  460-482 C2H2-type zinc finger
  477-497 Zinc-finger double domain
  488-510 C2H2-type zinc finger
  488-510 Zinc finger, C2H2 type
  490-510 C2H2-type zinc finger
  502-526 Zinc-finger double domain
  516-538 Zinc finger, C2H2 type
  530-554 Zinc-finger double domain
  544-563 Zinc finger, C2H2 type
  545-566 C2H2-type zinc finger
  546-554 C2H2-type zinc finger
  558-581 Zinc-finger double domain
  572-594 Zinc finger, C2H2 type
  588-609 Zinc-finger double domain
  600-622 Zinc finger, C2H2 type
  600-622 C2H2-type zinc finger
  614-638 Zinc-finger double domain
  628-650 Zinc finger, C2H2 type
  628-650 C2H2-type zinc finger
  642-666 Zinc-finger double domain
  656-674 C2H2-type zinc finger
  670-695 Zinc-finger double domain
  685-707 Zinc finger, C2H2 type
  685-707 C2H2-type zinc finger
  699-724 Zinc-finger double domain
  712-726 C2H2-type zinc finger
  713-735 Zinc finger, C2H2 type
  713-735 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MGPQGARRQAFLAFGDVTVDFTQKEWRLLSPAQRALYREVTLENYSHLVSLGILHSKPEL   60
  61 IRRLEQGEVPWGEERRRRPGPCAGIYAEHVLRPKNLGLAHQRQQQLQFSDQSFQSDTAEG  120
 121 QEKEKSTKPMAFSSPPLRHAVSSRRRNSVVEIESSQGQRENPTEIDKVLKGIENSRWGAF  180
 181 KCAERGQDFSRKMMVIIHKKAHSRQKLFTCRECHQGFRDESALLLHQNTHTGEKSYVCSV  240
 241 CGRGFSLKANLLRHQRTHSGEKPFLCKVCGRGYTSKSYLTVHERTHTGEKPYECQECGRR  300
 301 FNDKSSYNKHLKAHSGEKPFVCKECGRGYTNKSYFVVHKRIHSGEKPYRCQECGRGFSNK  360
 361 SHLITHQRTHSGEKPFACRQCKQSFSVKGSLLRHQRTHSGEKPFVCKDCERSFSQKSTLV  420
 421 YHQRTHSGEKPFVCRECGQGFIQKSTLVKHQITHSEEKPFVCKDCGRGFIQKSTFTLHQR  480
 481 THSEEKPYGCRECGRRFRDKSSYNKHLRAHLGEKRFFCRDCGRGFTLKPNLTIHQRTHSG  540
 541 EKPFMCKQCEKSFSLKANLLRHQWTHSGERPFNCKDCGRGFILKSTLLFHQKTHSGEKPF  600
 601 ICSECGQGFIWKSNLVKHQLAHSGKQPFVCKECGRGFNWKGNLLTHQRTHSGEKPFVCNV  660
 661 CGQGFSWKRSLTRHHWRIHSKEKPFVCQECKRGYTSKSDLTVHERIHTGERPYECQECGR  720
 721 KFSNKSYYSKHLKRHLREKRFCTGSVGEASS
Interface Residues: 219, 222, 225, 246, 247, 248, 249, 250, 252, 253, 254, 257, 259, 274, 275, 276, 277, 278, 280, 281, 282, 292, 302, 303, 304, 305, 306, 307, 308, 309, 310, 313, 314, 317, 318, 330, 331, 332, 333, 334, 336, 337, 358, 359, 360, 361, 362, 364, 365, 367, 368, 370, 371, 383, 385, 386, 387, 388, 389, 390, 393, 414, 415, 416, 417, 418, 419, 420, 421, 424, 442, 443, 444, 445, 446, 449, 455, 469, 471, 473, 474, 477, 481, 498, 499, 500, 501, 502, 505, 527, 530, 555, 557, 558, 561, 583, 586, 589, 611, 613, 614, 617, 639, 640, 641, 642, 645, 667, 669, 670, 673, 677, 695, 696, 698, 699, 702, 724, 725, 726, 727, 730
3D-footprint Homologues: 8ssq_A, 8ssu_A, 1ubd_C, 8cuc_F, 1tf3_A, 7n5w_A, 7w1m_H, 4x9j_A, 2drp_D, 1f2i_J, 2gli_A, 1g2f_F, 1tf6_A, 5und_A, 2i13_A, 6wmi_A, 8h9h_G, 2lt7_A, 6dta_B, 3uk3_C, 1llm_D, 4m9v_C, 6a57_A, 2kmk_A, 6ml4_A, 5yj3_D, 7txc_E, 5yel_A, 4pog_H, 6u9q_A, 6jnm_A, 7y3l_A, 5v3j_F, 1mey_C, 6blw_A, 5ei9_F, 5kl3_A, 5k5i_A, 6e94_A, 2jpa_A, 2wbs_A, 5k5l_F, 5kkq_D, 8gn3_A, 7eyi_G, 7y3m_I, 7ysf_A
Binding Motifs: UN0610.1 ykkryCyrrGAr
UN0610.2 yCyrrGAr
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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